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Association of Maternal Neurodevelopmental Risk Alleles With Early-Life Exposures
Key Points Question Are maternal polygenic risk scores for neurodevelopmental disorders associated with early-life exposures? Findings In this population-based cohort study of 7921 mothers, polygenicExpand
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Using Genetics to Examine a General Liability to Childhood Psychopathology
Psychiatric disorders show phenotypic as well as genetic overlaps. There are however also marked developmental changes throughout childhood. We investigated the extent to which, for a full range ofExpand
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A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK Biobank
Psychiatric disorders are highly heritable and associated with a wide variety of social adversity and physical health problems. Using genetic liability (rather than phenotypic measures of disease) asExpand
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Using genetics to examine a general liability to childhood psychopathology
Background Psychiatric disorders show phenotypic as well as genetic overlaps. Factor analyses of child and adult psychopathology have found that phenotypic overlaps largely can be explained by aExpand
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Early maternal perceived stress and children’s BMI: longitudinal impact and influencing factors
BackgroundMaternal perceived stress has been discussed to contribute to the development of childhood overweight. Our aim was to investigate the longitudinal relationship of early maternal perceivedExpand
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ADHD and depression: investigating a causal explanation.
BACKGROUND Attention-deficit hyperactivity disorder (ADHD) is associated with later depression and there is considerable genetic overlap between them. This study investigated if ADHD and ADHD geneticExpand
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A cross-disorder MR-pheWAS of 5 major psychiatric disorders in UK Biobank
Psychiatric disorders are highly heritable and associated with a wide variety of social adversity and physical health problems. Using genetic liability (rather than phenotypic measures of disease) asExpand
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Is genetic liability to ADHD and ASD causally linked to educational attainment?
Background Individuals with Attention Deficit Hyperactivity Disorder (ADHD) or Autism Spectrum Disorder (ASD) are at risk of poor educational outcomes. Parental educational attainment has also beenExpand
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