B. Lell

Publications188
h-index49
Citations9,255
Highly Influential Citations299
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Decreased atopy in children infected with Schistosoma haematobium: a role for parasite-induced interleukin-10
BACKGROUND Most of the effort directed at understanding the role infections have in preventing allergy has focused on bacteria and viruses and their ability to divert the immune system towards… Expand
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A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants.
BACKGROUND The candidate malaria vaccine RTS,S/AS01 reduced episodes of both clinical and severe malaria in children 5 to 17 months of age by approximately 50% in an ongoing phase 3 trial. We studied… Expand
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Low Interleukin-12 Activity in Severe Plasmodium falciparum Malaria
ABSTRACT We compared interleukin-12 (IL-12) and other cytokine activities during and after an acute clinical episode in a matched-pair case-control study of young African children who presented with… Expand
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Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria
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Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine.
BACKGROUND The RTS,S/AS01 vaccine targets the circumsporozoite protein of Plasmodium falciparum and has partial protective efficacy against clinical and severe malaria disease in infants and… Expand
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Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe.
BACKGROUND The replication-competent recombinant vesicular stomatitis virus (rVSV)-based vaccine expressing a Zaire ebolavirus (ZEBOV) glycoprotein was selected for rapid safety and immunogenicity… Expand
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Virulence factors and genotypes of Staphylococcus aureus from infection and carriage in Gabon.
Staphylococcus aureus isolates from developed countries have been extensively analyzed with respect to their virulence patterns and clonal relatedness but there is only sparse information on the… Expand
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Interferon-gamma responses are associated with resistance to reinfection with Plasmodium falciparum in young African children.
The contribution of T cell-mediated responses was studied with regard to resistance to reinfection in groups of Gabonese children participating in a prospective study of severe and mild malaria due… Expand
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Merozoite surface antigen 1 and 2 genotypes and rosetting of Plasmodium falciparum in severe and mild malaria in Lambaréné, Gabon.
We present a case-control study to investigate the distribution of Plasmodium falciparum genotypes in patients with severe and mild malaria. We compared clinical and parasitological data with the… Expand
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The role of red blood cell polymorphisms in resistance and susceptibility to malaria.
In regions highly endemic for Plasmodium falciparum malaria, red cell polymorphisms that confer resistance to severe disease are widespread. Sickle cell trait, alpha-thalassemia, glucose-6-phosphate… Expand
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