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Properties of a baboon lymphotropic herpesvirus related to Epstein‐Barr virus
Antigenic comparison with Epstein‐Barr virus showed that the baboon herpesvirus and EBV shared cross‐reacting viral capsid antigens (VCA), and preliminary molecular hybridization studies showed only approximately 40% homology between viral DNA of baboon cell lines and DNA of EBV derived from P3HR‐1 cells.
Reorganization and expansion of the nidoviral family Arteriviridae
An updated, amended, and improved arterivirus taxonomy is outlined based on current data and non-Latinized binomial species names are introduced to replace all current species names to clearly differentiate them from virus names, which remain largely unchanged.
Antibodies reacting with human T‐lymphotropic retrovirus (HTLV‐1) or related antigens in lymphomatous and healthy hamadryas baboons
- A. Voevodin, B. Lapin, L. A. Y Akovleva, T. I. Ponomaryeva, T. Oganyan, E. N. Razmadze
- Biology, MedicineInternational journal of cancer
- 15 November 1985
The sera of lymphomatous and healthy hamadryas baboons of the main, lymphoma‐prone Sukhumi stock were tested for antibodies reacting with HTLV‐1 antigens in the indirect immunofluorescence test, and the prevalence of anti‐HTLV positives increased by age, reaching its maximum at 5–15 years, and showed no significant sex‐related variation.
Effects of aging on hypothalamic–pituitary–adrenal system function in non-human primates
Use of Nonhuman Primates in Cancer Research
- B. Lapin
- MedicineJournal of medical primatology
- 1 December 1982
A short historical review of the use of primates in cancer research is presented followed by a review of various forms of neoplasma observed in the oldest existing Primate Center. Special attention…
The establishment of continuous lymphoblastoid suspension cell cultures from hematopoietic organs of baboon (Papio hamadryas) with malignant lymphoma.
Transforming activity and antigenicity of an Epstein-Barr-like virus from lymphoblastoid cell lines of baboons with lymphoid disease.
- H. Rabin, R. Neubauer, R. Hopkins, É. Dzhikidze, Z. V. Shevtsova, B. Lapin
- Biology, MedicineIntervirology
Two lymphoblastoid cell lines established from baboons with lymphoid disease released virus with in vitro transforming activity for lymphocytes of several primate species including humans and the virus was neutralized by anti-MA positive baboon and human sera.
Spontaneous and Experimental Hepatitis A in Old World Monkeys
Virologic, serologic, biochemical, and morphological data characterizing spontaneous hepatitis A in cynomolgus macaques and green monkeys are reported, and this experimental model of HA in macaques can be used for vaccine and anti‐viral preparation testing.
The Sukhumi primate monkey model for viral lymphomogenesis: high incidence of lymphomas with presence of STLV-I and EBV-like virus.
These animal models seem to be very suitable for the elucidation of the pathogenesis of human HTLV-I associated T-cell leukemia/lymphoma and might be further on used for therapeutical and preventative studies.
Protective effect and the therapeutic index of indralin in juvenile rhesus monkeys
Indralin has a significant radioprotective effect against radiation and has a high therapeutic index in rhesus monkeys, thus resulting in a less severe course of acute radiation syndrome.