B. La Scola

Publications448
h-index76
Citations27,300
Highly Influential Citations1,151
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Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
View on Elsevier
The 1.2-Megabase Genome Sequence of Mimivirus
TLDR
The size and complexity of the Mimivirus genome challenge the established frontier between viruses and parasitic cellular organisms and this new sequence data might help shed a new light on the origin of DNA viruses and their role in the early evolution of eukaryotes.
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Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.
BACKGROUND Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry accurately identifies both selected bacteria and bacteria in select clinical situations. It has not…
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Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study
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Giant Marseillevirus highlights the role of amoebae as a melting pot in emergence of chimeric microorganisms
TLDR
It is proposed that amoebae are “melting pots” of microbial evolution where diverse forms emerge, including giant viruses with complex gene repertoires of various origins.
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Laboratory diagnosis of rickettsioses: current approaches to diagnosis of old and new rickettsial diseases
TLDR
Every rickettsial species may have pathogenic potential, provided that its reservoir arthropod is capable of biting humans, and this minireview is restricted to these organisms.
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The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae.
TLDR
Comparisons of the vector-host ecology of these organisms suggest that the utilization of host-restricted vectors is associated with accelerated rates of genome degradation and may explain why human pathogens transmitted by specialist vectors are outnumbered by zoonotic agents, which use vectors of broad host ranges.
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Gene-sequence-based criteria for species definition in bacteriology: the Bartonella paradigm.
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Microbial culturomics: paradigm shift in the human gut microbiome study.
TLDR
Culturomics complements metagenomics by overcoming the depth bias inherent in metagenomic approaches, and identifies 174 species never described previously in the human gut.
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rpoB Gene Sequencing for Identification of Corynebacterium Species
TLDR
In order to propose a method for strain identification which does not require sequencing of the complete rpoB sequence, an area with a high degree of polymorphism is identified, bordered by conserved sequences that can be used as universal primers for PCR amplification and sequencing.
View on ASMUSA
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