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Synthesis and Antidiabetic Activity of 2‐Amino [5′(4‐Sulfonylbenzylidine)‐2,4‐thiazolidinedione] ‐7‐chloro‐6‐fluorobenzothiazole.
A new series of 2-amino[5'(4-sulphonylbenzylidine)-2,4-thiazolidinedione]-7-chloro-6-fluorobenzothiazole were synthesized The structures of the compounds were confirmed by UV-Vis, IR and NMR
Cardioprotective effect of ascorbic acid on doxorubicin-induced myocardial toxicity in rats
TLDR
Evidence is provided for the usefulness of the ascorbic acid as a cardioprotective agent because it significantly protected the myocardium from the toxic effect of dox by increasing the levels of antioxidant enzymes such as GSH, SOD, and CAT toward normal and decreased theLevel of MDA, CPK, LDH, AST, and ALT as compared with dox-treated rats.
Antihyperglycemic and Antihyperlipidemic Activity of Plectranthus Amboinicus on Normal and Alloxan-Induced Diabetic Rats
TLDR
Investigation in normal and alloxan-induced diabetic rats demonstrated that ethanol extract of Plectranthus amboinicus leaves possesses hypoglycemic and antihyperlipidemic effects mediated through the restoration of the functions of pancreatic tissues and insulinotropic effect.
Protective role of Phyllantus niruri extract in doxorubicin-induced myocardial toxicity in rats
TLDR
Results suggest a cardioprotective effect of P. niruri due to its antioxidant properties against doxorubicin (Dox)-induced myocardial toxicity in rats.
Cardioprotective effect of Saraca indica against cyclophosphamide induced cardiotoxicity in rats: A biochemical, electrocardiographic and histopathological study
TLDR
The biochemical, ECG and histopathology reports support the cardioprotective effect of Saraca indica which could be attributed to antioxidant activity.
Evaluation of Antiinflammatory Activity of Centratherum anthelminticum (L) Kuntze Seed
TLDR
The results suggest that petroleum ether and alcoholic extracts may exert antiinflammatory activity through prostaglandin inhibition, reduced myeloperoxidase and antitransudation.
Diuretic activity of extracts of Mimusops elengi Linn. bark
TLDR
A potent diuretic and electrolyte excretion activity in alcoholic extract of M. elengi bark is observed, which is similar to that observed in chloroform and petroleum ether extracts.
Alcoholic leaf extract of Plectranthus amboinicus regulates carbohydrate metabolism in alloxan-induced diabetic rats
TLDR
Evidence of the antidiabetic activity of Plectranthus amboinicus leaf extract in alloxan-induced diabetic rats is provided, mediated through the regulation of carbohydrate metabolic enzyme activities.
Antidiabetic and antihyperlipidemic activity of Premna latifolia extract in streptozotocin-induced diabetic rats
TLDR
This study substantiates that the alcoholic extract of Premna latifolia normalizes the blood glucose, insulin, lipid profile by regulating pancreatic and hepatic enzyme levels in diabetic rats.
Hepatoprotective Effect of Cissus quadrangularis Stem Extract Against Rifampicin-induced Hepatotoxicity in Rats
TLDR
The results of the present study indicated the hepatoprotective effect of methanol extract of Cissus quadrangularis which might be ascribable to its antioxidant property due to the presence of β-carotene.
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