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Salinity and drought tolerance of mannitol‐accumulating transgenic tobacco
Tobacco plants (Nicotiana tabacum L.) were transformed with a mannitol-1-phosphate dehydrogenase gene resulting in mannitol accumulation. Experiments were conducted to determine whether mannitolExpand
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Prevalence of PIK3CA mutations and the SNP rs17849079 in Arab breast cancer patients
Carcinomas initiate and progress due to genetic and epigenetic alterations in epithelial cells. However, recently, these alterations have also been reported in stromal fibroblasts. TheExpand
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The molecular significance of methylated BRCA1 promoter in white blood cells of cancer-free females
BackgroundBRCA1 promoter methylation has been detected in DNA from peripheral blood cells of both breast cancer patients and cancer-free females. However, the pathological significance of thisExpand
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A novel X‐linked disorder with developmental delay and autistic features
Genomic duplications that lead to autism and other human diseases are interesting pathological lesions since the underlying mechanism almost certainly involves dosage sensitive genes. We aim toExpand
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High prevalence of deleterious BRCA1 and BRCA2 germline mutations in arab breast and ovarian cancer patients
PurposeThe BRCA1 and BRCA2 (BRCA) genes are heavily involved in mammalian cell DNA repair processes. Germline pathogenic mutations in BRCA increase the lifetime risk of developing breast and/orExpand
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Non-invasive Molecular Detection of Minimal Residual Disease in Papillary Thyroid Cancer Patients
Background: Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy. Serum thyroglobulin (Tg) levels are used to monitor PTC treatment response and recurrences however, in aboutExpand
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Noninvasive Digital Detection of Fetal DNA in Plasma of 4-Week-Pregnant Women following In Vitro Fertilization and Embryo Transfer
The discovery of cell-free fetal DNA (cfDNA) circulating in the maternal blood has provided new opportunities for noninvasive prenatal diagnosis (NIPD). However, the extremely low levels of cfDNAExpand
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Methylation of BRCA1 and MGMT genes in white blood cells are transmitted from mothers to daughters
BackgroundConstitutive methylation of tumor suppressor genes are associated with increased cancer risk. However, to date, the question of epimutational transmission of these genes remains unresolved.Expand
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Association of Marginal Leaf Scorch with Sodium Accumulation in Salt-stressed Peach
The effect ofspecific ion toxicity during salt stress was tested in the present study. The experiment was repeated twice, in 1996 and 1998, with 'Nemaguard' peach seedlings and rooted cuttings grownExpand
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Allele-specific Emulsion PCR (asePCR) as a Liquid Biopsy Method for Residual Tumor Detection
Amac Bu calismada kanser hastalarinin kan plazmasinda sirkulasyondaki hucresiz tumor DNA’sinin  (ctDNA) saptanisina yonelik alel-spesifik bir emulsiyon polimeraz zincir reaksiyonu (asePCR) teknigiExpand
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