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MicroRNA-663 inhibits the proliferation, migration and invasion of glioblastoma cells via targeting TGF-β1.
Cell migration and invasion are key processes involved during tumor metastasis. Recently, microRNAs (miRs) have been demonstrated to play important roles in the regulation of cancer metastasis.Expand
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Overexpression of RKIP Inhibits Cell Invasion in Glioma Cell Lines through Upregulation of miR-98
Raf-1 kinase inhibitor protein (RKIP) is a tumor and metastasis suppressor in cancer cells. MicroRNAs (miRNAs) have been suggested to play a vital role in tumor initiation and progression byExpand
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Aberrant NEAT1 expression is associated with clinical outcome in high grade glioma patients
Long noncoding RNA (lncRNA) NEAT1 has been reported to play critical roles in various human tumor entities and related to the survival of patients with malignancies. However, little is known aboutExpand
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PAX6, a novel target of miR-335, inhibits cell proliferation and invasion in glioma cells.
Paired box 6 (PAX6), a highly conserved transcription factor, is important in glioma. However, the molecular mechanisms involved remain unclear. The present study demonstrated that the expression ofExpand
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Identification of Novel Predictive Markers for the Prognosis of Pancreatic Ductal Adenocarcinoma
This study demonstrated that klotho gene expression was significantly lower whereas miR-504 and phospho-IGF-1R levels were significantly higher in PDAC than in normal pancreatic tissues. miR-504Expand
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Signal Factors Secreted by 2D and Spheroid Mesenchymal Stem Cells and by Cocultures of Mesenchymal Stem Cells Derived Microvesicles and Retinal Photoreceptor Neurons
We aim to identify levels of signal factors secreted by MSCs cultured in 2D monolayers (2D-MSCs), spheroids (spheroids MSCs), and cocultures of microvesicles (MVs) derived from 2D-MSCs or spheroidExpand
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MicroRNA-30a increases the chemosensitivity of U251 glioblastoma cells to temozolomide by directly targeting beclin 1 and inhibiting autophagy
  • J. Xu, H. Huang, +4 authors Jian Xi
  • Chemistry, Medicine
  • Experimental and therapeutic medicine
  • 29 March 2018
Temozolomide (TMZ) is one of the most commonly used drugs for the clinical treatment of glioblastomas. However, it has been reported that treatment with TMZ can induce autophagy, which leads to tumorExpand
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Severe thoracic spinal fracture-dislocation without neurological symptoms and costal fractures: a case report and review of the literature
IntroductionOnly a high-energy force can cause thoracic spinal fracture-dislocation injuries, and such injuries should always be suspected in patients with polytrauma. The injury is usuallyExpand
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Diagnostic test accuracy of Spot and Plusoptix photoscreeners in detecting amblyogenic risk factors in children: a systemic review and meta‐analysis
Amblyopia is a permanent visual impairment developed in early childhood. Recently, instrument‐based photoscreeners have been widely used for vision screening to detect amblyopia risk factors, whichExpand
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Clinical value of homocysteine , cystatin C and FFA levels in patients with ischemic cerebrovascular disease
patients with ischemic cerebrovascular disease Bing Jiang1, Lisheng Ren1, Shaoyan Zhang1, Pan Wang1, Kaiqiu Chu* 1 Department of Clinical Laboratory, Medical College of Qingdao University, Qingdao,Expand
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