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Epilepsy after penetrating head injury. I. Clinical correlates
TLDR
Of 421 veterans who had penetrating brain wounds in Vietnam 15 years ago, 53% had posttraumatic epilepsy, and one-half of those still had seizures 15 years after injury, and Phenytoin therapy in the first year after injury did not prevent later seizures.
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Language dominance in partial epilepsy patients identified with an fMRI reading task
TLDR
An fMRI reading paradigm can identify language dominance in frontal and temporal areas and clinical visual interpretation is comparable to quantitative ROI analysis.
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Botulinum toxin A and chronic low back pain
TLDR
Pavertebral administration of botulinum toxin A in patients with chronic low back pain relieved pain and improved function at 3 and 8 weeks after treatment.
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Brain metastasis in breast cancer: a comprehensive literature review
TLDR
The molecular features of breast cancers most likely to develop brain metastases and the potential use of these predictive molecular alterations for patient management and future therapeutic targets are addressed.
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Brain metastasis from ovarian cancer: a systematic review
TLDR
Factors that significantly increased the survival were younger age at the time of ovarian cancer diagnosis and brain metastasis diagnosis, lower grade of the primary tumor, higher KPS score and multimodality treatment for the brain metastases.
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Treatment of Painful Limbs/Moving Extremities with Botulinum Toxin Type A Injections
TLDR
2 patients with PLMT in whom analgesic multipharmacy failed to relieve their severe lower limb pain are described in whom Botulinum toxin type A (Botox, Allergan, Inc.) resulted in both pain relief and improvement of involuntary movements.
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Congenital mirror movements. Abnormal organization of motor pathways in two patients.
TLDR
Study of patients with congenital mirror movements finds abnormalities in maps of motor and premovement potentials and in PET scans are consistent with aberrant organization of motor representation areas and corticospinal pathways with ipsilateral as well as contralateral control of voluntary movement.
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Predicting posttraumatic epilepsy in penetrating head injury.
Using data derived from a 15-year follow-up study of 520 veterans surviving penetrating brain wounds received in the Vietnam war, we have developed a predictive formula and tables for posttraumatic…
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Botulinum toxin A for spasticity, muscle spasms, and rigidity
TLDR
It is concluded that botulinum toxin A is effective against the disabling effects of spasticity and rigidity and the treatment was well tolerated.
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Sialorrhea: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins
TLDR
The clinical features, anatomy and physiology of sialorrhea are described, as well as a review of the world literature on medical treatment using Yale University’s search engine; including but not limited to Medline and Erasmus.
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