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  • Influence
Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency
BLyS (also called BAFF, TALL-1, THANK, and zTNF4), a TNF superfamily member, binds two receptors, TACI and BCMA, and regulates humoral immune responses [1-7]. These two receptors also bind APRILExpand
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Evidence that c-myc mediated apoptosis does not require wild-type p53 during lymphomagenesis.
Deregulation of c-myc, frequently implicated in oncogenesis, is associated with increased cell proliferation and also cell death. Similarly, the p53 tumor suppressor gene commonly mutated in humanExpand
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Evidence that p53 and bcl-2 are regulators of a common cell death pathway important for in vivo lymphomagenesis.
Multistep lymphomagenesis involves the deregulation of oncogenes and inactivation of tumor suppressor genes resulting in altered rates of proliferation as well as apoptotic cell death in tumor cells.Expand
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Mechanism of melphalan crosslink enhancement by misonidazole pretreatment.
Sensitization of Chinese hamster ovary cells to melphalan (L-PAM) toxicity by prior treatment with misonidazole (MISO, 5 mM, 2 hr, hypoxic conditions, 37 degrees C) is associated with increasedExpand
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The use of herbs as anticancer agents.
  • B. Hsu
  • Medicine
  • The American journal of Chinese medicine
  • 1980
The effectiveness of certain herbal drugs as anticancer agents has been studied for many years in China by researchers in various disciplines. The preparations discussed here are: Camptothecin andExpand
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The functional basis of c-myc and bcl-2 complementation during multistep lymphomagenesis in vivo.
Oncogenes are known to be deregulated by chromosomal translocations occurring at high frequency in specific malignancies. Among the most well characterized of these are c-myc, associated with theExpand
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Thrombogenic activity of mouse and human tumors: effects on platelets, coagulation, and fibrinolysis, and possible significance for metastases
Twelve mouse tumors and 29 human malignancies were assayed in vitro for their capacity to aggregate platelets and induce release of radiolabelled serotonin, and for their ability to coagulate bloodExpand
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The bcl-2 oncogene: apoptosis and neoplasia.
Cloning of the t(14;18) translocation breakpoint resulted in the identification of a new putative oncogene, which mapped to 18q21, termed bcl-2. The t(14;18) resulted in inappropriately high levelsExpand
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The roles of macrophage (M phi) and PGE-2 in postburn immunosuppression.
  • L. Yang, B. Hsu
  • Medicine
  • Burns : journal of the International Society for…
  • 1 April 1992
Postburn immunosuppression in mice with full skin thickness burns was assessed after Con A stimulation of splenic lymphocytes. The immunosuppression was detected within 24 h of injury and was maximalExpand
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