• Publications
  • Influence
The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics
The Carbohydrate-Active Enzyme (CAZy) database is a knowledge-based resource specialized in the enzymes that build and breakdown complex carbohydrates and glycoconjugates. Expand
  • 4,401
  • 403
  • PDF
A core gut microbiome in obese and lean twins
The human distal gut harbours a vast ensemble of microbes (the microbiota) that provide important metabolic capabilities, including the ability to extract energy from otherwise indigestible dietaryExpand
  • 5,810
  • 279
  • PDF
The carbohydrate-active enzymes database (CAZy) in 2013
The Carbohydrate-Active Enzymes database (CAZy; http://www.cazy.org) provides online and continuously updated access to a sequence-based family classification linking the sequence to the specificity and 3D structure of the enzymes that assemble, modify and breakdown oligo- and polysaccharides. Expand
  • 3,311
  • 153
  • PDF
A classification of glycosyl hydrolases based on amino acid sequence similarities.
  • B. Henrissat
  • Medicine, Biology
  • The Biochemical journal
  • 1 December 1991
The amino acid sequences of 301 glycosyl hydrolases and related enzymes have been compared. A total of 291 sequences corresponding to 39 EC entries could be classified into 35 families. Only tenExpand
  • 2,811
  • 126
Glycosyltransferases: structures, functions, and mechanisms.
Glycosyltransferases catalyze glycosidic bond formation using sugar donors containing a nucleoside phosphate or a lipid phosphate leaving group. Only two structural folds, GT-A and GT-B, have beenExpand
  • 1,228
  • 97
  • PDF
Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium
Fusarium species are among the most important phytopathogenic and toxigenic fungi. To understand the molecular underpinnings of pathogenicity in the genus Fusarium, we compared the genomes of threeExpand
  • 1,146
  • 81
  • PDF
Structures and mechanisms of glycosyl hydrolases.
The wealth of information provided by the recent structure determinations of many different glycosyl hydrolases shows that the substrate specificity and the mode of action of these enzymes areExpand
  • 1,644
  • 78
Metabolic Reconstruction for Metagenomic Data and Its Application to the Human Microbiome
We derive the functional and metabolic potential of a microbial community metagenome directly from short sequence reads. Expand
  • 811
  • 77
  • PDF
Structural and sequence-based classification of glycoside hydrolases.
The diversity of oligo- and polysaccharides provides an abundance of biological roles for these carbohydrates. The enzymes hydrolysing these compounds, the glycoside hydrolases, therefore mediate aExpand
  • 1,439
  • 72
Genome sequence of the lignocellulose degrading fungus Phanerochaete chrysosporium strain RP78
White rot fungi efficiently degrade lignin, a complex aromatic polymer in wood that is among the most abundant natural materials on earth. These fungi use extracellular oxidative enzymes that areExpand
  • 791
  • 72
  • PDF