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Reflex and chemical responses of tracheal submucosal glands in piglets.
TLDR
The data suggest that reflex responses of submucosal glands are weak during early postnatal development, however, tracheal submukosal glands do respond to exogenously administered cholinergic substances and tachykinin peptides.
Tracheal smooth muscle responses to substance P and neurokinin A in the piglet.
TLDR
Biochemical analyses demonstrated a significant increase in tracheal NEP activity in comparably aged piglets over the first 10 wk of life, indicating a cholinergic contribution to these responses at all ages.
Maturation of respiratory reflex responses in the piglet.
TLDR
It is demonstrated that between 2 and 10 wk of life, piglets exhibit developmental changes in the reflex responses of airway smooth muscle situated in the larger airways in response to irritant and C-fiber but not chemoreceptor stimulation.
Development of cholinergic innervation and muscarinic receptor subtypes in piglet trachea.
TLDR
It is speculated that the weak tracheal smooth muscle contraction observed during the first week of life is in part secondary to immature G protein function.
Regulation of expiratory muscles during postnatal development in anesthetized piglets.
TLDR
It is concluded that during postnatal development the rib cage and abdominal expiratory muscle responses to chemostimulation are coupled to each other and parallel those of the DIA and the presence of vagal afferents attenuates the drive to both inspiratory and expiratories motoneurons under the current experimental conditions.
Recurrent hypoxic exposure and reflex responses during development in the piglet.
TLDR
It is concluded that the response of the anesthetized newborn piglet to recurrent hypoxia is dominated by increasing inhibition of phrenic neuroelectrical output during successive hypoxic exposures.
Central effects of endothelin on respiratory output during development.
TLDR
The results suggest that endothelin-1 release may cause ventilatory depression mediated through endothelins-A receptors located in the chemosensitive areas of the ventrolateral medulla.
Carotid bodies and ventilatory response to hypoxia in aminophylline‐treated piglets
TLDR
It is concluded that aminophylline prevents respiratory depression during late hypoxia, however, in the absence of afferent input generated by the carotid bodies, aminopylline does not reverse respiratory depression induced by Hypoxia in anesthetized newborn piglets.
Response of upper airway and chest wall muscles to selective brain stem hypoxia in the newborn.
TLDR
It is concluded that, despite eliciting the known central respiratory depression, BS hypoxia causes an increase in the respiratory drive to an UA airway muscle, which elicits a selective rather than a generalized respiratory muscle depression.