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Genome-Wide Survey of SNP Variation Uncovers the Genetic Structure of Cattle Breeds
Data show that cattle have undergone a rapid recent decrease in effective population size from a very large ancestral population, possibly due to bottlenecks associated with domestication, selection, and breed formation. Expand
A Validated Whole-Genome Association Study of Efficient Food Conversion in Cattle
- W. Barendse, A. Reverter, R. Bunch, B. Harrison, W. Barris, M. B. Thomas
- Biology, Medicine
- 1 July 2007
Using whole-genome association, it is found that DNA variants in or near proteins contributing to the background use of energy of the cell were 10 times as common as those affecting appetite and body-mass homeostasis and suggests that certain subsets of micro-RNA are more important for the regulation of this trait. Expand
An enhanced linkage map of the sheep genome comprising more than 1000 loci.
Inspection of ruminant linkage maps indicates that the genomic coverage by the current sheep linkage map is comparable to that of the available cattle maps. Expand
Accuracy of prediction of genomic breeding values for residual feed intake and carcass and meat quality traits in Bos taurus, Bos indicus, and composite beef cattle.
Although accuracies of genomic predictions for 19 traits including feed efficiency, growth, and carcass and meat quality traits in beef cattle are low, genomic selection would still be beneficial for traits that are hard to improve by conventional selection, such as tenderness and residual feed intake. Expand
Genome wide signatures of positive selection: The comparison of independent samples and the identification of regions associated to traits
- W. Barendse, B. Harrison, R. Bunch, Merle B Thomas, L. Turner
- Biology, Medicine
- BMC Genomics
- 24 April 2009
The signals of selection identified through population divergence in the Bovine HapMap project are compared to those found in an independent sample of cattle from Australia, finding 12 regions that had additive effects on the traits residual feed intake, beef yield or intramuscular fatness measured in the Australian sample. Expand
A genome-wide association study of meat and carcass traits in Australian cattle.
Chromosomal regions containing DNA variation affecting the traits intramuscular fat percentage (IMF), meat tenderness measured as peak force to shear the LM (LLPF), and rump fat measured at the… Expand
The growth hormone 1 GH1:c.457C>G mutation is associated with intramuscular and rump fat distribution in a large sample of Australian feedlot cattle.
The GH1:c.457C>G exon 5 missense mutation in the bovine growth hormone 1 (GH1) gene that causes the replacement of leucine (L) with valine (V) was investigated in 1027 cattle with primarily Angus and… Expand
A genome-wide association study of tick burden and milk composition in cattle
The results agree in general with the phenotypic correlations between tick counts and milk component yield and suggest that selection on markers for tick burden or milk component yields may have no undesirable effect on the other trait. Expand
Evidence for pleiotropism and recent selection in the PLAG1 region in Australian Beef cattle.
The C allele appears to mark a mutation that has been selected almost to fixation in the B. taurus breeds studied here and introduced into Brahman cattle during grading up and selected to a frequency of 0.52 despite its negative effects on fertility. Expand
Variation at the Calpain 3 gene is associated with meat tenderness in zebu and composite breeds of cattle
BackgroundQuantitative Trait Loci (QTL) affecting meat tenderness have been reported on Bovine chromosome 10. Here we examine variation at the Calpain 3 (CAPN3) gene in cattle, a gene located within… Expand