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Ancient and Novel Small RNA Pathways Compensate for the Loss of piRNAs in Multiple Independent Nematode Lineages
Small RNA pathways act at the front line of defence against transposable elements across the Eukaryota. In animals, Piwi interacting small RNAs (piRNAs) are a crucial arm of this defence. However,… Expand
Biology of the phylum nematomorpha.
It is made the case that a lot of basic information remains to be uncovered in the understanding of nematomorphs, and the recent advances in information and techniques lay a solid foundation for the future study of this unique group of parasites. Expand
The phylogenetic position of Rhopalura ophiocomae (Orthonectida) based on 18S ribosomal DNA sequence analysis.
- B. Hanelt, D. Van Schyndel, C. Adema, L. A. Lewis, E. Loker
- Biology, Medicine
- Molecular biology and evolution
- 1 November 1996
Using the models of minimum evolution and parsimony, phylogenetic analyses were undertaken and the results lend support to the following hypotheses about orthonectids: (1) orthonECTids are more closely aligned with triploblastic metazoan taxa than with the protist or diploblasts considered in this analysis. Expand
Detection of Schistosoma mansoni in Biomphalaria using nested PCR.
A nested polymerase chain reaction (PCR) protocol was developed for detecting the presence of Schistosoma mansoni sporocysts in intermediate host snails of the genus Biomphalaria and has utility in determining if snails in endemic areas bear prepatent or inactive infections and in assessing the degree of compatibility between local snail and schistosome populations. Expand
Introgressive hybridization of human and rodent schistosome parasites in western Kenya
Hybridization between a trematode parasite of humans and its sister species, Schistosoma mansoni, in a natural hybrid zone in western Kenya showed that hybrids between the two species occur in nature, are fertile and produce viable offspring through backcrosses with S. mansoni. Expand
Redescription and compilation of Nearctic freshwater Nematomorpha (Gordiida), with the description of two new species
The two new species described here raise the number of gordiids known from the Nearctic region to 17, and from the 30 species names used for Nearctic nematomorphs, 15 are regarded as valid species. Expand
Cryptic species of hairworm parasites revealed by molecular data and crowdsourcing of specimen collections.
By using crowdsourcing, citizen scientists have collected and submitted samples of Gordius cf. Expand
An anomaly against a current paradigm – extremely low rates of individual fecundity variability of the Gordian worm (Nematomorpha: Gordiida)
- B. Hanelt
- Biology, Medicine
- 22 December 2008
Male body length appeared to be limited by intensity, whereas females showed no length limitation by crowding, suggesting that within gordiid populations the offspring of the next generation are contributed nearly equally by females. Expand
A bacterial artificial chromosome library for Biomphalaria glabrata, intermediate snail host of Schistosoma mansoni.
- C. Adema, M. Luo, +14 authors E. Loker
- Biology, Medicine
- Memorias do Instituto Oswaldo Cruz
- 1 October 2006
A high quality bacterial artificial chromosome (BAC) library is produced for analysis of the genome of Biomphalaria glabrata, a field isolate that is susceptible to several strains of Schistosoma mansoni that was selfed for two generations to reduce haplotype diversity in the offspring. Expand
Early Differential Gene Expression in Haemocytes from Resistant and Susceptible Biomphalaria glabrata Strains in Response to Schistosoma mansoni
Gene set enrichment analysis revealed that genes involved in mitochondrial electron transport, ubiquinone biosynthesis and electron carrier activity were consistently up-regulated in resistant snails but down- regulated in susceptible snails, which supports the hypothesis that schistosome-resistant snails recognize schistOSomes and mount an appropriate defence response, while in schisto-susceptible snails the parasite suppresses this defence response early in infection. Expand