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Hyperinsulinaemia as a Risk Factor for Developing Benign Prostatic Hyperplasia
Objective: To determine the validity coefficient of the total prostate gland volume as an expression of the transition zone (TZ) volume. To test the hypothesis of hyperinsulinaemia as a causal factor… Expand
Components of the metabolic syndrome—risk factors for the development of benign prostatic hyperplasia
- J. Hammarsten, B. Högstedt, N. Holthuis, D. Mellström
- Prostate Cancer and Prostatic Diseases
- 1 March 1998
The purpose of the present study was to perform a BPH risk factor analysis in men, relating the prostate gland volume to components of the metabolic syndrome and to identify clues to the etiology of… Expand
Clinical, anthropometric, metabolic and insulin profile of men with fast annual growth rates of benign prostatic hyperplasia.
The purpose of this study was to test the hypothesis of a causal relationship between high insulin levels and the development of benign prostatic hyperplasia (BPH) and to determine the clinical,… Expand
Cancer risk in humans predicted by increased levels of chromosomal aberrations in lymphocytes: Nordic study group on the health risk of chromosome damage.
Cytogenetic assays in peripheral blood lymphocytes (PBL) have been used extensively to survey the exposure of humans to genotoxic agents. The conceptual basis for this has been the hypothesis that… Expand
Hyperinsulinaemia: a prospective risk factor for lethal clinical prostate cancer.
Previous studies have suggested that hyperinsulinaemia and other components of metabolic syndrome are risk factors for clinical prostate cancer. This prospective study tested the hypothesis that… Expand
Clinical, haemodynamic, anthropometric, metabolic and insulin profile of men with high‐stage and high‐grade clinical prostate cancer
Aims: Previous studies have shown that non‐insulin‐dependent diabetes mellitus (NIDDM), hypertension, atherosclerotic disease manifestations, tallness, obesity, dyslipidaemia, hyperuricaemia,… Expand
A prospective study of cancer incidence in a cohort examined for allergy
In order to assess the association between atopy and cancer risk, a cohort of 6593 skin‐prick‐tested patients was established. Among atopic subjects, no overall increased cancer risk was found, but… Expand
Cytogenetic effects in rotogravure printers exposed to toluene (and benzene).
Comparing 21 rotogravure printers exposed to toluene (medians: time-weighted air level 150 mg/m3, blood toluene 1.6 mumole/l) and 21 unexposed controls (median blood toluene less than or equal to… Expand
Exposure to polycyclic aromatic hydrocarbons and genotoxic effects on nonsmoking Swedish road pavement workers.
- B. Järvholm, G. Nordström, +4 authors C. Bergendahl
- Environmental Science, Medicine
- Scandinavian journal of work, environment…
- 1 April 1999
OBJECTIVES The objective of this study was to investigate exposure to polycyclic aromatic hydrocarbons (PAH) from asphalt fumes among Swedish road pavement workers and determine whether any effects… Expand
Gasoline pump mechanics had increased frequencies and sizes of micronuclei in lymphocytes stimulated by pokeweed mitogen.
- B. Högstedt, A. Holmén, A. Karlsson, G. Raihle, K. Nillius, K. Vestlund
- Biology, Medicine
- Mutation research
- 1 May 1991
Fifteen gasoline pump mechanics and 15 controls were investigated with the lymphocyte micronucleus assay and also with differential count of leukocytes in the peripheral blood. The lymphocytes were… Expand