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The epidemiology of gastroenteropancreatic neuroendocrine tumors.
In this article, updated analyses of the National Cancer Institute Surveillance, Epidemiology and End Results (SEER) registry (1973-2007) are presented and compared with epidemiologic GEP-NET dataExpand
Bronchopulmonary neuroendocrine tumors
Bronchopulmonary neuroendocrine tumors (BP‐NETs) comprise ≈20% of all lung cancers and represent a spectrum of tumors arising from neuroendocrine cells of the BP‐epithelium. Although they shareExpand
Chromogranin A—Biological Function and Clinical Utility in Neuro Endocrine Tumor Disease
BackgroundNeuroendocrine tumors (NETs) are a form of cancer that differ from other neoplasia in that they synthesize, store, and secrete peptides, e.g., chromogranin A (CgA) and amines. A criticalExpand
Neuroendocrine tumor epidemiology
The National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) program has proven to be a significant resource in US neuroendocrine tumor (NET) epidemiology. Norway also holds aExpand
Review article: somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine (carcinoid) tumours
Background  The discovery of somatostatin (SST) and the synthesis of a variety of analogues constituted a major therapeutic advance in the treatment of gastroenteropancreatic neuroendocrineExpand
Neuroendocrine Tumors of the Gallbladder: An Evaluation and Reassessment of Management Strategy
Background Gallbladder neuroendocrine tumors (GB-NETs) represent only 0.5% of all NETs, and little is known about their biological behavior. We sought to provide an overview of the current state ofExpand
Long-Term Serotonin Administration Induces Heart Valve Disease in Rats
Background—The purpose of this study was to investigate whether rats dosed with serotonin develop changes similar to those seen in human carcinoid heart disease. Methods and Results—TenExpand
Neuroendocrine tumors of the diffuse neuroendocrine system
Purpose of review Neuroendocrine tumors (previously referred to as carcinoids) are ill-understood, enigmatic malignancies that, although slow-growing compared with adenocarcinomas, can behaveExpand
Serotonin and fluoxetine modulate bone cell function in vitro
Recent studies have proposed a role for serotonin and its transporter in regulation of bone cell function. In the present study, we examined the in vitro effects of serotonin and the serotoninExpand
The clinical relevance of chromogranin A as a biomarker for gastroenteropancreatic neuroendocrine tumors.
Chromogranin A, although it exhibits limitations, is currently the most useful general tumor biomarker available for use in the diagnosis and management of gastroenteropancreatic neuroendocrineExpand