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The gut microbiota influences blood-brain barrier permeability in mice
The intestinal microbiota helps to maintain the integrity of the blood-brain barrier in fetal and adult mice. The Gut Microbiota and the Blood-Brain Barrier The blood-brain barrier is an importantExpand
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Olfactory Functions Are Mediated by Parallel and Hierarchical Processing
How the human brain processes the perception, discrimination, and recognition of odors has not been systematically explored. Cerebral activations were therefore studied with PET during five differentExpand
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Smelling of Odorous Sex Hormone-like Compounds Causes Sex-Differentiated Hypothalamic Activations in Humans
The anatomical pathways for processing of odorous stimuli include the olfactory nerve projection to the olfactory bulb, the trigeminal nerve projection to somatosensory and insular cortex, and theExpand
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Visual memory, visual imagery, and visual recognition of large field patterns by the human brain: functional anatomy by positron emission tomography.
We measured the regional cerebral blood flow (rCBF) in 11 healthy volunteers with PET (positron emission tomography). The main purpose was to map the areas of the human brain that changed rCBF duringExpand
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Role of sodium channel inhibition in neuroprotection: effect of vinpocetine
Vinpocetine (ethyl apovincaminate) discovered during the late 1960s has successfully been used in the treatment of central nervous system disorders of cerebrovascular origin for decades. The increaseExpand
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Limbic reductions of 5-HT1A receptor binding in human temporal lobe epilepsy
Objective: To test the hypothesis that in mesial temporal lobe epilepsy (MTLE) there is involvement outside of mesial structures and that this involvement affects serotonin systems, thus suggesting aExpand
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Odorant differentiated pattern of cerebral activation: Comparison of acetone and vanillin
Whether different odorous compounds (odorants) are processed by different cerebral circuits is presently unknown. A first step to address this complicated issue is to investigate how the cerebralExpand
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Response latencies of visual cells in macaque areas V1, V2 and V5
The response to moving light and dark slits was recorded from a total of 94 cells in V1, V2, and V5 (MT) in 9 anesthetized and paralyzed macaque monkeys (M. fascicularis). Using the spatial lagExpand
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Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: A comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride
PET measurements of stimulant‐induced dopamine (DA) release are typically performed with antagonist radioligands that bind to both the high‐ and low‐affinity state of the receptor. In contrast, anExpand
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Preparation of highly specific radioactivity [18F]flumazenil and its evaluation in cynomolgus monkey by positron emission tomography.
A straightforward method for the preparation of no-carrier-added (n.c.a.) [18F]flumazenil via standard nucleophilic radiofluorination of the corresponding nitro-analog Ro 15-2344 has been developed.Expand
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