• Publications
  • Influence
Incidence, pathogenesis, and management of sepsis: an overview.
Sepsis is a complex condition that occurs as a result of the systemic manifestation of infection. It is associated with high morbidity and mortality risks for critically ill patients. Assessment andExpand
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Comparison of pneumococcal polysaccharide and CRM197-conjugated pneumococcal oligosaccharide vaccines in young and elderly adults.
Conjugation of carbohydrate antigens to protein carriers significantly improves the immune response to many carbohydrates. In order to evaluate the potential for this approach to improve theExpand
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Acute care nurse practitioner education: enhancing performance through the use of clinical simulation.
Full-body patient simulators have been used for a number of years to educate nurse anesthetists and anesthesiologists. These lifelike mannequins operate from a sophisticated computerized system withExpand
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The ratio of arginine to dimethylarginines is reduced and predicts outcomes in patients with severe sepsis*
Objectives: Arginine deficiency may contribute to microvascular dysfunction, but previous studies suggest that arginine supplementation may be harmful in sepsis. Systemic arginine availability can beExpand
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Using business intelligence to improve performance.
Cleveland Clinic's enterprise performance management program offers proof that comparisons of actual performance against strategic objectives can enable healthcare organization to achieve rapidExpand
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Incidence and distribution of experimental metastases in mutant mice with defective organ microenvironments (genotypes Sl/Sld and W/Wv).
Mice carrying mutations at the Sl (steel) and W (dominant white spotting) loci develop abnormalities on 3 migratory embryonic stem cell populations: hematopoietic stem cells, neural crest-derivedExpand
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Brachial artery reactivity in patients with severe sepsis: an observational study
IntroductionUltrasound measurements of brachial artery reactivity in response to stagnant ischemia provide estimates of microvascular function and conduit artery endothelial function. We hypothesizedExpand
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Productivity improvement: Catholic Health East reaps rewards.
Healthcare organizations that want to implement a productivity program should: Name an executive champion to lead the initiative. Develop a business model. Establish a productivity steering committeeExpand
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