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Interactions between econazole, a broad-spectrum antimicrobic substance, and topically active glucocorticoids.
Econazole is a broad-spectrum antimicrobic substance which acts by permeabilizing the cell membranes. Glucocorticoids by their surface activity may counteract this effect by protecting the cellExpand
Influence of ultraviolet light, various temperatures, and zinc ions on anthralin (dithranol). Biochemical and chemical investigations.
The changes of anthralin under various physical conditions (temperature, ultraviolet irradiation) were investigated by biochemical assay (inhibition of G-6-PDH activity), by oxygen monitor (increasedExpand
D-penicillamine and enzymatic activities.
The influence of incubation with D-penicillamine on pure enzyme preparations and on enzymatic activities of serum and skin homogenates was investigated. Three of the nine enzymatic activities studiedExpand
Evaluation of econazoie by Warburg assay; Comparison with other antimicrobials
In manometrischen Untersuchungen (Warburg‐Versuch) wurden die Dosis‐Wirkungs‐Kurven von Econazol auf Candida albicans, Saccharomyces cerevisiae und Staphylococcus aureus bestimmt. Hierdurch ließ sichExpand
The Influence of D-Penicillamine on Enzymatic Activities: Glucose-6-phosphate Dehydrogenase. Correlation with Serum Levels Measured in Humans
The influence of D-penicillamine on glucose-6-phosphate dehydrogenase of yeast (pure enzyme), human hemolysate, and human skin homogenate were determined. In high concentrations, D-penicillamineExpand
In Vitro evaluation of methotrexate and azathioprine for antipsoriatic activity
  • W. Raab, B. Gmeiner
  • Chemistry, Medicine
  • Archives of Dermatological Research
  • 29 August 1975
SummaryThe effects of methotrexate and azathioprine, two drugs used in antipsoriatic therapy, on oxygen consumption of surviving human skin and on enzymatic activities of human skin homogenates wereExpand
D-Penicillamine in dermatology: Influence on enzymatic activities of human skinin vitro
  • W. Raab, B. Gmeiner
  • Biology, Medicine
  • Archives of Dermatological Research
  • 14 November 1975
SummaryByin vitro assay, 6 important enzymatic activities of human skin homogenates were determined following an incubation withD-penicillamine in concentrations between 10−4 and 10 mg/ml, i.e. 67 ×Expand
Inhibition of glucose-6-phosphate dehydrogenase activity by betamethasone and three of its esters with dermatological importance
  • W. Raab, B. Gmeiner
  • Chemistry, Medicine
  • Archives of Dermatological Research
  • 12 September 1975
SummaryBetamethasone, betamethasone-17-valerate, betamethasone-17-benzoate, and betamethasone-17,21-diproprionate were investigated for their inhibitory action on glucose-6-phosphate dehydrogenaseExpand
Enzyme inhibition in human skin homogenates by hydrocortisone, hydrocortisone acetate and hydrocortisone butyrate
SummaryIn fresh human skin homogenates, the activities of four enzymes, lactate dehydrogenase (LDH), glucose-6-phosphate dehydrogenase (G-6-PDH), “acid” phosphatase (AcP), and “leucineExpand