• Publications
  • Influence
Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease
This study investigated cerebral glucose metabolism in very early Alzheimer's disease, before a clinical diagnosis of probable Alzheimer's disease is possible, using [18F]fluorodeoxyglucose positronExpand
  • 1,532
  • 72
Disability caused by minor head injury.
The authors studied 538 patients who had sustained minor head trauma, which was defined as a history of unconsciousness of 20 minutes or less, a Glasgow Coma Scale score of 13 to 15, andExpand
  • 988
  • 27
Stepping over obstacles: dividing attention impairs performance of old more than young adults.
BACKGROUND Tripping over an obstacle is a common cause of falls in the elderly. An earlier study of abilities to avoid stepping on suddenly appearing obstacles found that, although healthy old adultsExpand
  • 289
  • 19
  • PDF
Adult attention deficit hyperactivity disorder: psychological test profiles in a clinical population.
Compared to attention deficit hyperactivity disorder (ADHD) in children, relatively little is known about the clinical characteristics of adults with persistent ADHD. We elected to use establishedExpand
  • 250
  • 16
Incidence of dementia and cognitive impairment, not dementia in the united states
Estimates of incident dementia, and cognitive impairment, not dementia (CIND) (or the related mild cognitive impairment) are important for public health and clinical care policy. In this paper, weExpand
  • 159
  • 16
A 30-Week Randomized Controlled Trial of High-Dose Tacrine in Patients With Alzheimer's Disease
Objective. —To evaluate the efficacy and safety of high-dose tacrine hydrochloride over 30 weeks in patients with probable Alzheimer's disease. Design. —A 30-week randomized, double-blind,Expand
  • 862
  • 13
Cerebral Glucose Metabolic Features of Parkinson Disease and Incident Dementia: Longitudinal Study
Longitudinal studies in nondemented Parkinson disease (PD) subjects offer an opportunity to study the earliest regional cerebral subcortical and cortical metabolic changes underlying incidentExpand
  • 154
  • 10
  • PDF
A preliminary evaluation of the cognitive and motor effects of pediatric HIV infection in Zairian children.
Fourteen asymptomatic HIV-infected Zairian children under 2 years of age displayed social and motor developmental deficits on the Denver Developmental Screening Test when compared with 20Expand
  • 153
  • 10
Moderate head injury: completing the clinical spectrum of brain trauma.
We have divided head injury into three categories based on the Glasgow Coma Scale (GCS) (severe, 3-8; moderate, 9-12; and minor, 13-15). In a previous report, we described significant disabilityExpand
  • 439
  • 9
Immediate Neuropsychological and Behavioral Benefits of Computerized Cognitive Rehabilitation in Ugandan Pediatric Cerebral Malaria Survivors
Objective: Our earlier studies on Ugandan children surviving cerebral malaria showed cognitive deficits mainly in attention and memory. We now present the first study in sub-Saharan Africa toExpand
  • 77
  • 9