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Parietal Lobe: From Action Organization to Intention Understanding
- L. Fogassi, P. Ferrari, B. Gesierich, S. Rozzi, F. Chersi, G. Rizzolatti
- Biology, PsychologyScience
- 29 April 2005
Inferior parietal lobule neurons were studied when monkeys performed motor acts embedded in different actions and when they observed similar acts done by an experimenter to allow the observer to understand the agent's intentions.
Anterior temporal lobe degeneration produces widespread network-driven dysfunction.
The findings provide a neurophysiological basis for the theory that semantic processing is orchestrated through interactions between a critical anterior temporal lobe hub and modality-selective processing nodes.
Asymmetric fMRI adaptation reveals no evidence for mirror neurons in humans
- A. Lingnau, B. Gesierich, A. Caramazza
- Biology, PsychologyProceedings of the National Academy of Sciences
- 16 June 2009
Failure to find cross-modal adaptation for executed and observed motor acts is not compatible with the core assumption of mirror neuron theory, which holds that action recognition and understanding are based on motor simulation.
A Novel Imaging Marker for Small Vessel Disease Based on Skeletonization of White Matter Tracts and Diffusion Histograms
To establish a fully automated, robust imaging marker for cerebral small vessel disease (SVD) and related cognitive impairment that is easy to implement, reflects disease burden, and is strongly…
The Perceived Onset Time of Self- and Other-Generated Actions
The results are consistent with the view that intentions are attributed to others but not to machines, and raise the interesting possibility that people attribute intentions to themselves in the same way as they do to others.
Microglia monitor and protect neuronal function through specialized somatic purinergic junctions
The junctions appear to provide a major site for microglia-neuron communication and may help to mediate the neuroprotective effects ofmicroglia after acute brain injury, and microglial processes at these junctions could potentially monitor and protect neuronal functions.
Incident lacunes preferentially localize to the edge of white matter hyperintensities: insights into the pathophysiology of cerebral small vessel disease.
The findings suggest that the mechanisms of lacunes and white matter hyperintensities are intimately connected and identify the edge of white matter Hyperintensity penumbra as a predilection site for lacunes.
Acute infarcts cause focal thinning in remote cortex via degeneration of connecting fiber tracts
- M. Duering, R. Righart, F. Wollenweber, V. Zietemann, B. Gesierich, M. Dichgans
- 21 April 2015
Primary degeneration of connected white matter tracts and remote cortex as key features of acute ischemic infarcts are identified and may have implications for the understanding of structural and functional reorganization after stroke.
What Role Does the Anterior Temporal Lobe Play in Sentence-level Processing? Neural Correlates of Syntactic Processing in Semantic Variant Primary Progressive Aphasia
- Stephen M. Wilson, A. DeMarco, M. Gorno-Tempini
- Psychology, BiologyJournal of Cognitive Neuroscience
- 1 May 2014
The findings indicate that spared syntactic processing in semantic PPA depends on preserved functionality of structurally intact left frontal regions and moderately atrophic left posterior temporal regions, but no functional reorganization was apparent as a consequence of anterior temporal atrophy and dysfunction.
Automated Morphological Analysis of Microglia After Stroke
- S. Heindl, B. Gesierich, Corinne Benakis, G. Llovera, M. Duering, A. Liesz
- BiologyFront. Cell. Neurosci.
- 19 April 2018
A fully automated image analysis tool, which enables the analysis of microglia morphology from a confocal Z-stack and providing up to 59 morphological features, and shows excellent accuracy and time efficacy compared to traditional analysis methods.