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CD4+ count-guided interruption of antiretroviral treatment.
TLDR
Episodic antiretroviral therapy guided by the CD4+ count significantly increased the risk of opportunistic disease or death from any cause, as compared with continuous antireteviral therapy, largely as a consequence of lowering theCD4+ cell count and increasing the viral load.
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Immune reconstitution inflammatory syndrome associated with Kaposi's sarcoma.
TLDR
In the clinical experience HAART could be successfully continued in those with IRIS-associated KS, and in patients with higher CD4 counts, KS-associated edema, and therapy with both protease inhibitors and non-nucleosides together.
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British HIV Association guidelines for the treatment of HIV‐1‐infected adults with antiretroviral therapy 2008
TLDR
The 2008 BHIVA Guidelines have been updated to incorporate all the new relevant information since the last iteration and all the peer-reviewed publications and important, potentially treatment-changing abstracts from the last 2 years have been reviewed.
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Increased numbers of acute hepatitis C infections in HIV positive homosexual men; is sexual transmission feeding the increase?
TLDR
This study was undertaken to determine whether within clinics, changes in the number of individuals being diagnosed with acute HCV infection were occurring and to ascertain risk factors for acquisition in these individuals.
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The role of immune suppression and HHV-8 in the increasing incidence of HIV-associated multicentric Castleman's disease.
TLDR
The incidence of HIV-associated Castleman's disease in HIV appears to occur more frequently in older HIV-positive individuals with well-preserved immune function, and is increasing.
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Multicenter study of human immunodeficiency virus-related germ cell tumors.
TLDR
Testicular seminoma occurs significantly more frequently in HIV-positive men than in the matched control population and should be treated in a similar manner to those in the HIV-negative population.
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Pulmonary Kaposi sarcoma in the era of highly active antiretroviral therapy
TLDR
Since the introduction of highly active antiretroviral therapy (HAART) there has been a dramatic reduction in the incidence of Kaposi sarcoma and an improvement in survival and the outcome in pulmonary KS (pKS) has also altered.
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British HIV Association, BASHH and FSRH guidelines for the management of the sexual and reproductive health of people living with HIV infection 2008
A Fakoya, H Lamba, N Mackie, R Nandwani, A Brown, EJ Bernard, C Gilling-Smith, C Lacey, L Sherr, P Claydon, S Wallage and B Gazzard British HIV Association (BHIVA), BHIVA Secretariat, Mediscript Ltd,…
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Increased proportion of CD16+ NK cells in the colonic lamina propria of inflammatory bowel disease patients, but not after azathioprine treatment
Aliment Pharmacol Ther 2011; 33: 115–126
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Treatment of HIV-associated invasive anal cancer with combined chemoradiation.
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