• Publications
  • Influence
Presence of a membrane bound pyroglutamyl amino peptidase degrading thyrotropin releasing hormone in rat brain
In the present work we studied the pattern of degradation of [3H-Pro]-TRH by soluble and membrane fractions from rat brain. Demonstration of the membrane bound or soluble nature of the activities wasExpand
  • 61
  • 4
Ribosome profiling reveals translation control as a key mechanism generating differential gene expression in Trypanosoma cruzi
BackgroundDue to the absence of transcription initiation regulation of protein coding genes transcribed by RNA polymerase II, posttranscriptional regulation is responsible for the majority of geneExpand
  • 77
  • 4
Sinorhizobium meliloti Fur-Like (Mur) Protein Binds a Fur Box-Like Sequence Present in the mntA Promoter in a Manganese-Responsive Manner
ABSTRACT In Sinorhizobium meliloti, the MurSm protein, a homologue of the ferric uptake regulator (Fur), mediates manganese-dependent regulation of the MntABCD manganese uptake system. In this study,Expand
  • 33
  • 4
Functional Genomic Characterization of mRNAs Associated with TcPUF6, a Pumilio-like Protein from Trypanosoma cruzi*
Trypanosoma cruzi is the protozoan parasite that causes Chagas disease or American trypanosomiasis. Kinetoplastid parasites could be considered as model organisms for studying factors involved inExpand
  • 47
  • 3
Vanadium polypyridyl compounds as potential antiparasitic and antitumoral agents: new achievements.
In the search for new therapeutic tools against diseases produced by kinetoplastid parasites five vanadyl complexes, [V(IV)O(L-2H)(phen)], including 1,10-phenanthroline (phen) and tridentateExpand
  • 98
  • 2
  • PDF
Trypanosoma cruzi: molecular characterization of TcPUF6, a Pumilio protein.
In trypanosomes regulation of gene expression occurs mainly at the post-transcriptional level. Pumilio proteins are RNA-binding proteins that modulate gene expression in lower and higher eukaryotes.Expand
  • 20
  • 2
The Trypanosoma cruzi nucleic acid binding protein Tc38 presents changes in the intramitochondrial distribution during the cell cycle
BackgroundTc38 of Trypanosoma cruzi has been isolated as a single stranded DNA binding protein with high specificity for the poly [dT-dG] sequence. It is present only in Kinetoplastidae protozoa andExpand
  • 11
  • 2
Design of vanadium mixed-ligand complexes as potential anti-protozoa agents.
In the search for new therapeutic tools against Chagas' disease (American Trypanosomiasis) four novel mixed-ligand vanadyl complexes, [V(IV)O(L(2)-2H)(L(1))], including a bidentate polypyridyl DNAExpand
  • 75
  • 1
Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents.
In the search for new therapeutic tools against Chagas' disease (American Trypanosomiasis) two series of new platinum(II) complexes with bioactive 5-nitrofuryl containing thiosemicarbazones asExpand
  • 62
  • 1
A novel vanadyl complex with a polypyridyl DNA intercalator as ligand: a potential anti-protozoa and anti-tumor agent.
In the search for new metal-based drugs for the treatment of tumoral and parasitic diseases a vanadyl complex, [V(IV)O(SO(4))(H2O)(2)(dppz)].2H(2)O, that includes the bidentate polypyridyl DNAExpand
  • 69
  • 1