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Amelotin—a Novel Secreted, Ameloblast-specific Protein
The identification of a novel ameloblast-specific gene, amelotin (AMTN), is described by differential display polymerase chain-reaction (DD-PCR) analysis of microdissected ameloblasts, odontoblast, dental pulp, and alveolar bone cells of 10-day-old mouse incisors to suggest a critical role in the formation of dental enamel.
Natural graft tissues and synthetic biomaterials for periodontal and alveolar bone reconstructive applications: a review
Various available natural tissues and biomaterial based bone replacement graft and membrane options used in periodontal regeneration applications are reviewed.
Collagen based barrier membranes for periodontal guided bone regeneration applications
Collagen membranes in GBR procedures have shown them to be effective and comparable with non-resorbable membranes with regards to clinical attachment gain, probing depth reduction and defect bone filling, and long-term clinical trials are required to further evaluate and confirm the efficacy of the available collagen barrier membranes for periodontal and bone regeneration use.
3. Protein-protein interactions of the developing enamel matrix.
Characterization of a Novel KRAB/C2H2Zinc Finger Transcription Factor Involved in Bone Development*
These studies, therefore, have identified a novel zinc finger transcription factor in bone that can modulate Runx2 activity and osteogenic differentiation.
Targeted Overexpression of Amelotin Disrupts the Microstructure of Dental Enamel
It is demonstrated that the overexpression of amelotin has a profound effect on enamel structure by disrupting the formation of Tomes' process and the orderly growth of enamel prisms.
Lumican is a major proteoglycan component of the bone matrix.