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Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient
Proper partitioning of the contents of a cell between two daughters requires integration of spatial and temporal cues. The anaphase array of microtubules that self-organize at the spindle midzoneExpand
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Radiation therapy of pineal region tumors: 25 new cases and a review of 208 previously reported cases.
PURPOSE Malignant pineal region tumors are rare neoplasms arising in midline structures of the brain. This report analyzes the influence of histology, tumor location, radiation dose, treatmentExpand
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Stereotaxic radiosurgery for brain metastases: the importance of adjuvant whole brain irradiation.
Stereotaxic radiosurgery delivered from a modified 4 MV linear accelerator was used to treat 47 brain metastases in 27 patients at Stanford. Response was assessed in 41 lesions. HistopathologiesExpand
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Mutations of the STK11 gene in sporadic gastric carcinoma.
Gastric carcinoma may occur sporadically or in association with hereditary diseases, such as Peutz-Jehgers syndrome (PJS). The PJS gene (named STK11 or LKB1) was mapped to 19p13.3 and recentlyExpand
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Intramedullary Ewing sarcoma of the spinal cord: consequences of molecular diagnostics. Case report.
Molecular biological techniques have begun to transform modern medicine. These techniques have shown promise in the pathological diagnosis of difficult or uncommon tumors. Accurate molecularExpand
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Telomerase activity in microdissected human gliomas.
Future improvements in the diagnosis and treatment of human gliomas might rely on obtaining more specific information concerning the biologic characteristics of individual tumor cells. Telomerase, aExpand
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Self-organization of intracellular gradients during mitosis
Gradients are used in a number of biological systems to transmit spatial information over a range of distances. The best studied are morphogen gradients where information is transmitted over manyExpand
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Mutation of the uracil DNA glycosylase gene detected in glioblastoma.
Despite extensive characterization of genetic changes in gliomas, the underlying etiology of these tumors remains largely unknown. Spontaneous DNA damage due to hydrolysis, methylation, and oxidationExpand
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Missense Mutation of the MET Gene Detected in Human Glioma
Multiple mechanisms, such as gene mutations, amplifications, and rearrangements, as well as perturbed mitogen and receptor function, are likely to contribute to glioma formation. The MET (also knownExpand
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