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Arginine Vasopressin in Advanced Vasodilatory Shock: A Prospective, Randomized, Controlled Study
Background—Vasodilatory shock is a potentially lethal complication of severe disease in critically ill patients. Currently, catecholamines are the most widely used vasopressor agents to support bloodExpand
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Microvascular and tissue oxygen gradients in the rat mesentery.
One of the most important functions of the blood circulation is O2 delivery to the tissue. This process occurs primarily in microvessels that also regulate blood flow and are the site of manyExpand
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Plasma viscosity regulates capillary perfusion during extreme hemodilution in hamster skinfold model.
Effect of increasing blood viscosity during extreme hemodilution on capillary perfusion and tissue oxygenation was investigated in the awake hamster skinfold model. Two isovolemic hemodilution stepsExpand
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Reversal of trauma-induced coagulopathy using first-line coagulation factor concentrates or fresh frozen plasma (RETIC): a single-centre, parallel-group, open-label, randomised trial.
BACKGROUND Effective treatment of trauma-induced coagulopathy is important; however, the optimal therapy is still not known. We aimed to compare the efficacy of first-line therapy using fresh frozenExpand
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The Effect of Fibrinogen Substitution on Reversal of Dilutional Coagulopathy: An In Vitro Model
Colloids and crystalloids are usually administered as treatment for hypovolemia in severely injured patients. However, dilution of clotting factors and platelets together with impaired fibrinogenExpand
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Capillary perfusion during ischemia-reperfusion in subcutaneous connective tissue and skin muscle.
Ischemia-reperfusion injury was investigated in terms of functional capillary density (FCD), capillary red blood cell velocity (cRBCv), and arteriolar and venular diameter after 4-h ischemia in theExpand
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The Effects of Progressive Anemia on Jejunal Mucosal and Serosal Tissue Oxygenation in Pigs
Anemia may promote intestinal hypoxia.We studied the effects of progressive isovolemic hemodilution on jejunal mucosal (PO2 muc), and serosal tissue oxygen tension (PO2 ser, Clark-type surfaceExpand
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Central Venous Catheter Colonization in Critically Ill Patients: A Prospective, Randomized, Controlled Study Comparing Standard with Two Antiseptic-Impregnated Catheters
In this prospective, randomized, controlled, unblinded study, we compared colonization rates of a standard, unimpregnated central venous catheter (CVC) with rates for silver-coated andExpand
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Vasomotion induces regular major oscillations in jejunal mucosal tissue oxygenation.
The mucosa of the small intestine has some unique microcirculatory features that may result in significant tissue oxygenation changes even under physiological conditions. To prove this hypothesis weExpand
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Capillary flow impairment and functional capillary density.
Functional capillary density is variable in both normal and diseased tissue. When this parameter is defined as the number of capillaries that possess red blood cell transit, changes in functionalExpand
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