• Publications
  • Influence
Gastric Helicobacters in Domestic Animals and Nonhuman Primates and Their Significance for Human Health
SUMMARY Helicobacters other than Helicobacter pylori have been associated with gastritis, gastric ulcers, and gastric mucosa-associated lymphoid tissue lymphoma in humans. These very fastidiousExpand
Colonization strategy of Campylobacter jejuni results in persistent infection of the chicken gut.
A novel colonization mechanism by escaping rapid mucosal clearance through short-term epithelial invasion and evasion, combined with fast replication in the mucus is suggested. Expand
Genome sequence of Helicobacter suis supports its role in gastric pathology
Although genes coding for some important virulence factors in H. pylori, such as the cytotoxin-associated protein (CagA), are not detected in the H. suis genome, homologs of other genes associated with colonization and virulence of H.pylori and other bacteria are present. Expand
Non-Helicobacter pylori helicobacters detected in the stomach of humans comprise several naturally occurring Helicobacter species in animals.
It is proposed to use the term 'gastric NHPH' to designate gastric spirals that are morphologically different from H. pylori when no identification is available at the species level. Expand
Butyricicoccus pullicaecorum in inflammatory bowel disease
Patients with inflammatory bowel disease have lower numbers of Butyricicoccus bacteria in their stools and administration of B pullicaecorum attenuates TNBS-induced colitis in rats and supernatant of B pulledicaECorum cultures strengthens the epithelial barrier function by increasing the TER. Expand
Gastric epithelial cell death caused by Helicobacter suis and Helicobacter pylori γ‐glutamyl transpeptidase is mainly glutathione degradation‐dependent
The mechanism used by H. suis to induce gastric epithelial cell damage is unraveled and GGT‐mediated generation of pro‐oxidant glutathione degradation products brings on cell damage and causes apoptosis or necrosis, dependent on the amount of extracellular glutATHione available as a GGT substrate. Expand
The local immune response of mice after Helicobacter suis infection: strain differences and distinction with Helicobacter pylori
The genetic background of the murine strain has a clear impact on the colonization ability of different H. suis strains and the immune response they evoke, and a predominant Th17 response was observed, accompanied by a mild Th2 response, which is different from the Th17/Th1 response evoked by H. pylori infection. Expand
Helicobacter suis Causes Severe Gastric Pathology in Mouse and Mongolian Gerbil Models of Human Gastric Disease
The possible involvement of this micro-organism in human gastric disease should not be neglected and it is suggested that mice and Mongolian gerbils infected with H. suis should be neglected. Expand
Non‐Helicobacter pylori Helicobacter Species in the Human Gastric Mucosa: A Proposal to Introduce the Terms H. heilmannii Sensu Lato and Sensu Stricto
Clinicians and clinical bacteriologists will continue to use the name H. heilmannii to refer to the group of long spiral shaped microorganisms although according to taxonomic rules it represents only one member of this group, but this is proposed to be introduced to avoid further confusion. Expand
Gastric De Novo Muc13 Expression and Spasmolytic Polypeptide-Expressing Metaplasia during Helicobacter heilmannii Infection
Findings indicate that H. heilmannii infection causes severe gastric pathologies and alterations in the expression pattern of gastric mucins, such as Muc6 and Muc13, as well as disrupting gastric homeostasis by inducing the loss of parietal cells, resulting in the development of mucous metaplasia. Expand