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Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis
TLDR
Although lesion size >5 cm was associated with a slightly higher EDSS at last follow-up, long-term prognosis in patients with disease duration >10 years was better compared with a population-based multiple sclerosis cohort matched for disease duration (EDSS 3.5; P < 0.001).
Imaging classification of autosomal dominant polycystic kidney disease: a simple model for selecting patients for clinical trials.
TLDR
A longitudinal mixed regression model to predict eGFR decline showed that log2HtTKV and age significantly interacted with time in typical patients, but not in atypical patients.
Deep Learning for Brain MRI Segmentation: State of the Art and Future Directions
TLDR
An overview of current deep learning-based segmentation approaches for quantitative brain MRI is provided and a critical assessment of the current state and likely future developments and trends is provided.
The RSNA Pediatric Bone Age Machine Learning Challenge.
TLDR
The RSNA Pediatric Bone Age Machine Learning Challenge showed how a coordinated approach to solving a medical imaging problem can be successfully conducted and will catalyze collaboration and development of ML tools and methods that can potentially improve diagnostic accuracy and patient care.
Temporal Annotation in the Clinical Domain
TLDR
The implementation and extension of ISO-TimeML for annotating a corpus of clinical notes, known as the THYME corpus, is discussed and a new annotation guideline has been developed, “the THyME Guidelines to ISO- timeML (THYME-Time ML)”.
Beneficial plasma exchange response in central nervous system inflammatory demyelination.
TLDR
Clinical and radiographic features that may aid in identifying patients with fulminant, steroid-refractory central nervous system inflammatory demyelinating disease attacks who are more likely to respond to PLEX are identified.
Perivenous demyelination: association with clinically defined acute disseminated encephalomyelitis and comparison with pathologically confirmed multiple sclerosis.
TLDR
The co-occurrence of perivenous and confluent demyelination in some individuals suggests pathogenic overlap between acute disseminated encephalomyelitis and multiple sclerosis and misclassification even with biopsy.
FLAIR histogram segmentation for measurement of leukoaraiosis volume
TLDR
It is concluded that the FLAIR‐histoseg method is an accurate and reproducible method for measuring leukoaraiosis and whole‐brain volume in elderly subjects.
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