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Reference genes for normalization: A study of rat brain tissue
Quantitative real‐time polymerase chain reaction (qPCR) has become a widely used tool in the search for disease genes. When examining gene expression with qPCR in psychiatric diseases, endogenousExpand
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Detection of brain-derived neurotrophic factor (BDNF) in rat blood and brain preparations using ELISA: Pitfalls and solutions
Quantification of endogenous brain-derived neurotrophic factor (BDNF) can be performed with an enzyme-linked immunosorbent assay (ELISA). Although BDNF has been determined in blood and brainExpand
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The effect of exercise on hippocampal volume and neurotrophines in patients with major depression--a randomized clinical trial.
BACKGROUND The hippocampal volume is reduced in patients with major depression. Exercise leads to an increased hippocampal volume in schizophrenia and in healthy old adults. The effect of exercise onExpand
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Inverse correlation of brain and blood BDNF levels in a genetic rat model of depression.
There is accumulating evidence that brain-derived neurotrophic factor (BDNF) plays a critical role in the pathophysiology of depression. Decreased serum levels have been reported in major depression,Expand
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  • Open Access
Neuropeptide S alters anxiety, but not depression-like behaviour in Flinders Sensitive Line rats: a genetic animal model of depression.
Neuropeptide S (NPS) and its receptor (NPSR) have been implicated in the mediation of anxiolytic-like behaviour in rodents. However, little knowledge is available regarding the NPS system inExpand
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  • Open Access
Dietary magnesium deficiency alters gut microbiota and leads to depressive-like behaviour.
OBJECTIVE Gut microbiota (GM) has previously been associated with alterations in rodent behaviour, and since the GM is affected by the diet, the composition of the diet may be an important factorExpand
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  • Open Access
Increased stress-evoked nitric oxide signalling in the Flinders sensitive line (FSL) rat: a genetic animal model of depression.
Stress engenders the precipitation and progression of affective disorders, while stress-related release of excitatory mediators is implicated in the degenerative pathology observed especially in theExpand
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  • Open Access
Differential expression of synaptic vesicle proteins after repeated electroconvulsive seizures in rat frontal cortex and hippocampus
Electroconvulsive therapy (ECT) remains the treatment of choice for patients with severe or drug‐resistant depressive disorders, yet the mechanism behind its efficacy and the effect onExpand
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The Chicken Serotonin Transporter Discriminates between Serotonin-selective Reuptake Inhibitors
The serotonin transporter (SERT) belongs to a family of sodium chloride-dependent transporters responsible for uptake of amino acids and biogenic amines from extracellular spaces. SERT represents theExpand
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  • Open Access
Binding characteristics of the 5‐HT2A receptor antagonists altanserin and MDL 100907
To study the 5‐HT2A receptors in the living human brain, using positron emission tomography (PET), two selective radiotracers are currently in use: [18F]altanserin and [11C]MDL 100907. It is,Expand
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