• Publications
  • Influence
Strategies and tools for the control/elimination of lymphatic filariasis.
Lymphatic filariasis infects 120 million people in 73 countries worldwide and continues to be a worsening problem, especially in Africa and the Indian subcontinent. Elephantiasis, lymphoedema, andExpand
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Effects of standard and high doses of ivermectin on adult worms of Onchocerca volvulus: a randomised controlled trial
BACKGROUND At present, control of onchocerciasis depends almost entirely on yearly treatments with 150 microg/kg ivermectin. We aimed to compare the effect of higher doses, more frequent doses, orExpand
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Onchocerca-Simulium complexes. I. Transmission of forest and Sudan-savanna strains of Onchocerca volvulus, from Cameroon, by Simulium damnosum from various West African bioclimatic zones.
(1966). Onchocerca-Simulium complexes. Annals of Tropical Medicine & Parasitology: Vol. 60, No. 3, pp. 318-336.
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The population dynamics of Onchocerca volvulus in the human host.
  • B. Duke
  • Biology, Medicine
  • Tropical medicine and parasitology : official…
  • 1 June 1993
The quantitative aspects of onchocerciasis that focus on the relationship between the number of adult female Onchocerca volvulus in the human host, the total numbers of microfilariae (mfs) in theExpand
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Microfilariae in the cerebrospinal fluid, and neurological complications, during treatment of onchocerciasis with diethylcarbamazine.
Microfilariae of Onchocerca volvulus were found in the cerebrospinal fluid (CSF) of 5/8 heavily infected onchocerciasis patients. During treatment with diethylcarbamazine citrate 10/11 patientsExpand
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Human onchocerciasis--an overview of the disease.
The general characteristics of Onchocerca volvulus infection and its transmission are outlined in this overview of human onchocerciasis. The pathogenic role of the microfilariae, producing lesions ofExpand
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Effects of three-month doses of ivermectin on adult Onchocerca volvulus.
Onchocerca volvulus worms in nodules from Guatemalan patients treated with four, eight, or 11 single doses of ivermectin (150 micrograms/kg of body weight) that were given once every three monthsExpand
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Genetic Selection of Low Fertile Onchocerca volvulus by Ivermectin Treatment
Background Onchocerca volvulus is the causative agent of onchocerciasis, or “river blindness”. Ivermectin has been used for mass treatment of onchocerciasis for up to 18 years, and recently thereExpand
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The embryogenesis of Onchocerca volvulus over the first year after a single dose of ivermectin.
Adult Onchocerca volvulus, extracted from nodules before, and at intervals of two weeks to 12 months after, a single 150 micrograms/kg dose of ivermectin, were examined longitudinally and byExpand
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