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The inhibition by disodium cromoglycate in vitro of anaphylactically induced histamine release from rat peritoneal mast cells.
- E. J. Kusner, B. Dubnick, D. J. Herzig
- Biology, MedicineThe Journal of pharmacology and experimental…
It is suggested that DSCG acts indirectly, inducing the formation of an unstable species in mast cells from a precursor present in a limited amount, using rat peritoneal mast cells as an example.
Distribution and metabolism of chlorphentermine-C14 in rats and mice.
BIOCHEMICAL AND PHARMACOLOGICAL STUDIES OF β‐PHENYLETHYLHYDRAZINE AND SELECTED RELATED COMPOUNDS
- Max Chessin, B. Dubnick, G. Leeson, C. C. Scott
- ChemistryAnnals of the New York Academy of Sciences
- 1 September 1959
Many hydrazines and hydrazides that had been synthesized for antitubercular activity in 1952 were re-examined as possible M A 0 inhibitors and special consideration was given to hydrazine analogues of phenylethylamine because of their close chemical relationship to many of the biogenic amines.
SYMPATHOMIMETIC PROPERTIES OF CHLORPHENTERMINE: METABOLISM, METABOLIC EFFECTS, INTERACTION WITH RESERPINE AND BIOGENIC AMINES
Comparison of rates of metabolism and lipid/aqueous distribution ratios of chlor phentermine and several closely related compounds suggested that the prolonged pharmacological effects of chlorphentermine may be attributable to the influence of the para -chlorine.
INHIBITION OF MONOAMINE OXIDASE BY 2‐METHYL‐3‐PIPERIDINOPYRAZINE
It is established that 2-methyl-3-piperidinopyrazine, a representative member of this new group of inhibitors, does indeed inhibit MA0 as judged by biochemical criteria.
AN EFFECT OF MONOAMINE OXIDASE INHIBITORS ON BRAIN SEROTONIN OF MICE IN ADDITION TO THAT RESULTING FROM INHIBITION OF MONOAMINE OXIDASE *
The observation that the serotonin level continues to increase in response to doses of phenelzine which exceed the dose required for complete inhibition of MA0 prompted this report.
CHEMISTRY AND PHARMACOLOGY OF MONOAMINE OXIDASE INHIBITORS: HYDRAZINE DERIVATIVES.
Effect of forms of vitamin B6 on acute toxicity of hydrazines.
The separation of 3H-Benzodiazepine binding sites in brain and of benzodiazepine pharmacological properties