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A Polycationic Brush Mediated Co-Delivery of Doxorubicin and Gene for Combination Therapy
The combination of drug and gene strategies for cancer therapy, has exhibited greater effectiveness than drug or gene therapy alone. In this paper, a coil-comb shaped polycationic brush was used as aExpand
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The Functions of BMP3 in Rabbit Articular Cartilage Repair
Bone morphogenetic proteins (BMPs) play important roles in skeletal development and repair. Previously, we found fibroblast growth factor 2 (FGF2) induced up-regulation of BMP2, 3, 4 in the processExpand
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Identification of Key Candidate Genes and Pathways in Endometrial Cancer by Integrated Bioinformatical Analysis
Endometrial Cancer is the most common female genital tract malignancy, its pathogenesis is complex, not yet fully described. To identify key genes of Endometrial Cancer we downloaded the gene chipExpand
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Minocycline attenuates streptomycin-induced cochlear hair cell death by inhibiting protein nitration and poly (ADP-ribose) polymerase activation
This study aimed to elucidate the protective effect of minocycline against streptomycin-induced damage of cochlear hair cells and its mechanism. Cochlear membranes were isolated from newborn WistarExpand
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Digoxin Enhances the Anticancer Effect on Non-Small Cell Lung Cancer While Reducing the Cardiotoxicity of Adriamycin
  • Yingying Wang, Q. Ma, +8 authors Dexin Kong
  • Chemistry, Medicine
  • Frontiers in Pharmacology
  • 28 February 2020
Digoxin is widely used to treat heart failure. Epidemiological studies suggested it might be used as an anticancer drug or sensitizing agent for cancer therapy. Adriamycin is a well-known anticancerExpand
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A collagen mimetic peptide-modified hyaluronic acid hydrogel system with enzymatically mediated degradation for mesenchymal stem cell differentiation.
We have successfully designed and synthesized a biomimetic hydrogel system with maleimide-modified hyaluronic acid (HA) as the backbone and conjugated it to the collagen mimetic peptideExpand
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Efficacy of zolpidem in promoting awakening from persistent vegetative state in patients with brain injury
Objective To investigate the effect of zolpidem in promoting awakening from persistent vegetative state in patients with brain injury and analyze the relation between the timing of drugExpand
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