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Detection of Brucella melitensis and Brucella abortus by DNA amplification.
- G. Baily, J. Krahn, B. Drasar, N. Stoker
- Biology, Medicine
- The Journal of tropical medicine and hygiene
- 1 August 1992
The test was shown to be sensitive, and specificity was demonstrated using DNA derived from a panel of Gram-negative pathogens, and there was no detectable difference between B. melitensis and B. abortus. Expand
Effects of Burkholderia pseudomallei and other Burkholderia species on eukaryotic cells in tissue culture.
Uptake was followed by the intracellular multiplication of B. pseudomallei and the induction of cell fusion and multinucleate giant cell formation and this ability may be important in the pathogenesis of both acute and chronic infection. Expand
Intestinal bacteria and the hydrolysis of glycosidic bonds.
The results are discussed in terms of the toxicological and pharmacological effects of various ingested glycosides and of the enterohepatic circulation of compounds by four laboratory animal species commonly used in toxicological studies. Expand
Obligatory Role of Gamma Interferon for Host Survival in a Murine Model of Infection with Burkholderia pseudomallei
- P. Santanirand, V. Harley, D. Dance, B. Drasar, G. Bancroft
- Biology, Medicine
- Infection and Immunity
- 1 July 1999
Results provide the first evidence of a host protective mechanism against B. pseudomallei in Taylor Outbred mice, and the rapid production of IFN-γ within the first day of infection determines whether the infection proceeds to an acute lethal outcome or becomes chronic. Expand
Studies on the intestinal flora. I. The bacterial flora of the gastrointestinal tract in healthy and achlorhydric persons.
The stomach was sterile in most fasting normal people; only in patients with gastric achlorhydria was any bacterial colonization of the stomach seen; in the people studied who had gastric acid, the upper small intestine was virtually free from bacteria except after a meal. Expand
FÆCAL BILE-ACIDS AND CLOSTRIDIA IN PATIENTS WITH CANCER OF THE LARGE BOWEL
The findings support the hypothesis that cancer of the large bowel is caused by high concentrations of bile-acid derivatives produced by certain anaerobic bacteria. Expand
International law and infectious diseases.
- B. Drasar
- 1 June 2001
The ways in which international law has attempted to deal with the spread of microbial diseases are outlined and the political dimensions of their activities are outlined. Expand
Response of toxigenic Vibrio cholerae 01 to physico-chemical stresses in aquatic environments.
Results suggest that toxigenic V. cholerae 01 are able to survive for extended periods in warm water containing no nutrients but having a salinity of 0.25-3.0% and a pH of around 8.0, which is sufficient for rapid growth in the absence of nutrients and under the same conditions for enhanced growth in their presence. Expand
CHOLERA AND ESTUARINE SALINITY IN CALCUTTA AND LONDON
Lab investigation has shown that Vibrio cholerae requires a salinity of at least 0·01% to survive beyond 24 h, and it is proposed that this constraint on waterborne transmission, together with the seasonal fluctuations of estuarine salinities, may explain the seasonality of cholera in estuarist cities. Expand
Hygiene in the home: relating bugs and behaviour.
- V. Curtis, A. Biran, K. Deverell, C. Hughes, K. Bellamy, B. Drasar
- Social science & medicine
- 1 August 2003
An in-depth, multidisciplinary study of carer and child hygiene in the domestic environment in the Wirral, UK, employed structured observation, surface swabbing for polio vaccine virus and enteric marker organisms, semi-structured interviews, projective interviews and focus group discussions to address particular risk practices. Expand