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The Molecular Taxonomy of Primary Prostate Cancer
There is substantial heterogeneity among primary prostate cancers, evident in the spectrum of molecular abnormalities and its variable clinical course. As part of The Cancer Genome Atlas (TCGA), we… Expand
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array
Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a custom Illumina… Expand
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data from a custom… Expand
A church-based intervention to promote informed decision making for prostate cancer screening among African American men.
- B. Drake, Rachel C. Shelton, T. Gilligan, J. Allen
- Journal of the National Medical Association
- 1 March 2010
OBJECTIVES This feasibility study developed and pilot tested an intervention to: (1) increase knowledge about prostate cancer screening; and (2) promote self-efficacy to participate in the informed… Expand
Dose response to vitamin D supplementation in African Americans: results of a 4-arm, randomized, placebo-controlled trial.
- K. Ng, J. B. Scott, +9 authors C. Fuchs
- The American journal of clinical nutrition
- 1 March 2014
BACKGROUND Association studies have suggested that lower circulating 25-hydroxyvitamin D [25(OH)D] in African Americans may partially underlie higher rates of cardiovascular disease and cancer in… Expand
EVALUATING COMMUNITY ENGAGEMENT IN RESEARCH: QUANTITATIVE MEASURE DEVELOPMENT.
- M. Goodman, V. S. Sanders Thompson, +5 authors D. Bowen
- Medicine, Psychology
- Journal of community psychology
Although the importance of community engagement in research has been previously established, there are few evidence-based approaches for measuring the level of community engagement in research… Expand
Effect of Vitamin D Supplementation on Blood Pressure in Blacks
Blacks have significantly higher rates of hypertension than whites, and lower circulating levels of 25-hydroxyvitamin D. There are few data about the effect of vitamin D3 (cholecalciferol)… Expand
Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context
Summary Long noncoding RNAs (lncRNAs) are commonly dysregulated in tumors, but only a handful are known to play pathophysiological roles in cancer. We inferred lncRNAs that dysregulate cancer… Expand
Impact of Vitamin D Supplementation on Inflammatory Markers in African Americans: Results of a Four-Arm, Randomized, Placebo-Controlled Trial
African Americans have a disproportionate burden of inflammation-associated chronic diseases such as cancer and lower circulating levels of 25-hydroxyvitamin D [25(OH)D]. The effect of vitamin D3… Expand
Prostate cancer disparities in South Carolina: early detection, special programs, and descriptive epidemiology.
- B. Drake, T. Keane, +5 authors J. Hebert
- Journal of the South Carolina Medical Association
Available evidence suggests that there may be qualitative differences in the natural history of PrCA by race. If this is true then additional etiologic research is needed to identify places in the… Expand