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Body mass index and colorectal cancer prognosis: a systematic review and meta-analysis
TLDR
Both obese and underweight patients with colorectal cancer have an increased risk of all-cause mortality, cancer-specific mortality, disease recurrence and worse disease-free survival compared to normal weight patients. Expand
Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications.
TLDR
Sarcopenia, as a marker of frailty, is an important risk factor in surgical patients but difficult to estimate using bedside testing, and CT scans, performed for preoperative staging, provide an opportunity to quantify lean muscle mass without additional cost or exposure to radiation and eliminate the inconvenience of further investigations. Expand
Is early hip fracture surgery safe for patients on clopidogrel? Systematic review, meta-analysis and meta-regression.
TLDR
Early surgery appears safe for patients with hip fracture though there may be a small increase in the rate of blood transfusion, however, larger prospective trials are required to confirm these findings. Expand
Surgical interventions for the treatment of sacrococcygeal pilonidal sinus disease in children: A systematic review and meta-analysis.
TLDR
Evidence for management of PNS in children is poor, and off-midline primary closure, minimally invasive techniques, and marsupialisation have the best outcomes. Expand
Systematic review of pre-operative exercise in colorectal cancer patients
TLDR
There is evidence that pre-operative exercise improves functional fitness, and to a lesser extent objectively measurable cardio-respiratory fitness prior to colorectal cancer resection, but there is no clear evidence at present that this improvement in fitness translates into reduced peri-operative risk or improved post-operative outcomes. Expand
A systematic review and meta‐regression analysis of prophylactic gabapentin for postoperative pain
TLDR
Gabapentin reduced pre‐operative anxiety and increased patient satisfaction on a 10‐point scale by a mean (95% CI) of 1.52 (0.78–2.26) points and 0.89 ( 0.22–1.57) points, p < 0.001 and p = 0.01, respectively. Expand
Fibrin glue for pilonidal sinus disease.
TLDR
Low-quality evidence that fibrin glue, as an adjunct to Limberg flap, may reduce postoperative pain and time to return to normal activities is found and it is uncertain whether use of fibr in glue affects the incidence of postoperative seroma. Expand
Preventive Acetaminophen Reduces Postoperative Opioid Consumption, Vomiting, and Pain Scores After Surgery: Systematic Review and Meta-Analysis
TLDR
This is the first review to describe a potential preventive effect of acetaminophen and well-conducted randomized controlled trials are necessary to substantiate the conclusions of this review. Expand
A systematic review of pre‐operative anaemia and blood transfusion in patients with fractured hips
TLDR
There were insufficient high‐quality studies to inform pre‐operative blood transfusion or the use of peri‐operative iron or erythropoietin, and there was no association of postoperative transfusion with mortality after adjusting for covariates. Expand
The Use of Cannabinoids in Colitis: A Systematic Review and Meta-Analysis.
TLDR
There is abundant preclinical literature demonstrating the anti-inflammatory effects of cannabinoid drugs in inflammation of the gut, and larger randomised controlled-trials are warranted. Expand
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