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The interaction between carrier rugosity and carrier payload, and its effect on drug particle redispersion from adhesive mixtures during inhalation.
The effectiveness of press-on forces (defined as the adhesive forces between drug and carrier particles) in relation to carrier payload as the result of collisions between carrier particles duringExpand
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The effect of carrier surface treatment on drug particle detachment from crystalline carriers in adhesive mixtures for inhalation.
In this study, the effect of lactose carrier surface treatment on drug particle detachment during inhalation has been investigated. Crystals of marketed brands of alpha lactose monohydrate brandsExpand
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The effect of carrier surface and bulk properties on drug particle detachment from crystalline lactose carrier particles during inhalation, as function of carrier payload and mixing time.
The effect of carrier payload and mixing time on the redispersion of drug particles from adhesive mixtures during inhalation for two different drugs (budesonide and disodium cromoglycate) has beenExpand
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A critical evaluation of the relevant parameters for drug redispersion from adhesive mixtures during inhalation.
In this paper, the parameters that are relevant to the drug redispersion from adhesive mixtures during inhalation are discussed and evaluated. The results obtained with air classifier technology giveExpand
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Spray freeze drying to produce a stable Delta(9)-tetrahydrocannabinol containing inulin-based solid dispersion powder suitable for inhalation.
The purpose of this study is to investigate whether spray freeze drying produces an inhalable solid dispersion powder in which Delta(9)-tetrahydrocannabinol (THC) is stabilised. Solutions of THC andExpand
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The effect of budesonide particle mass on drug particle detachment from carrier crystals in adhesive mixtures during inhalation.
The different fine particle fractions (FPFs) that are obtained, when different dry powder inhalers (DPIs) are used for the same powder formulation at the same flow rate, is the result of differentExpand
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Adhesive mixtures for powder inhalation
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Adhesive mixtures for powder inhalation: The effect of carrier (surface and bulk) properties, carrier payload and mixing conditions on the performance of adhesive mixtures for inhalation
Toediening van geneesmiddelen via de longen is gecompliceerd, omdat de farmaca in het algemeen laag gedoseerd (in microgrammen) word. Tevens kunnen alleen deeltjes tussen de 1 en 5 micrometer kunnenExpand
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