The Transcriptional Landscape of the Mammalian Genome
- Piero Carninci, T. Kasukawa, Y. Hayashizaki
- BiologyScience
- 2 September 2005
Detailed polling of transcription start and termination sites and analysis of previously unidentified full-length complementary DNAs derived from the mouse genome provide a comprehensive platform for the comparative analysis of mammalian transcriptional regulation in differentiation and development.
Genome-Wide Analysis of the World's Sheep Breeds Reveals High Levels of Historic Mixture and Strong Recent Selection
- J. Kijas, J. Lenstra, B. Dalrymple
- Biology, MedicinePLoS Biology
- 1 February 2012
Genomic structure in a global collection of domesticated sheep reveals a history of artificial selection for horn loss and traits relating to pigmentation, reproduction, and body size.
A Genome Wide Survey of SNP Variation Reveals the Genetic Structure of Sheep Breeds
- J. Kijas, D. Townley, H. Raadsma
- BiologyPLoS ONE
- 3 March 2009
Sheep are characterised by weak phylogeographic structure, overlapping genetic similarity and generally low differentiation which is consistent with their short evolutionary history, and even a small panel of markers may be suitable for applications such as traceability.
A universal protein–protein interaction motif in the eubacterial DNA replication and repair systems
- B. Dalrymple, K. Kongsuwan, G. Wijffels, N. Dixon, P. A. Jennings
- BiologyProceedings of the National Academy of Sciences…
- 25 September 2001
Comparison of the eubacterial, eukaryotic, and archaeal sliding clamp binding motifs suggests that the basic interactions have been conserved across the evolutionary landscape.
Conservation of the regulatory subunit for the Clp ATP-dependent protease in prokaryotes and eukaryotes.
- S. Gottesman, C. Squires, T. Foster
- BiologyProceedings of the National Academy of Sciences…
- 1 May 1990
The high degree of similarity among the ClpA-like proteins suggests that Clp-like proteases are likely to be important participants in energy-dependent proteolysis in prokaryotic and eukaryotic cells.
The sheep genome illuminates biology of the rumen and lipid metabolism
- Yu Jiang, Min Xie, B. Dalrymple
- Biology, MedicineScience
- 6 June 2014
A genome for ewe and ewe Sheep-specific genetic changes underlie differences in lipid metabolism between sheep and other mammals, and may have contributed to the production of wool. Jiang et al.…
High osmolarity improves the electro-transformation efficiency of the gram-positive bacteria Bacillus subtilis and Bacillus licheniformis
- G. Xue, Jennifer S. Johnson, B. Dalrymple
- Biology
- 1999
A microRNA catalog of the developing chicken embryo identified by a deep sequencing approach.
- Evgeny A. Glazov, P. Cottee, W. Barris, Robert J. Moore, B. Dalrymple, M. Tizard
- BiologyGenome Research
- 1 June 2008
A bioinformatics pipeline was developed to distinguish authentic mature miRNA sequences from other classes of small RNAs and short RNA fragments represented in the sequencing data and detected almost all of the previously known chicken miRNAs and their respective miRNA* sequences.
Regulatory impact factors: unraveling the transcriptional regulation of complex traits from expression data
- A. Reverter, N. Hudson, S. Nagaraj, M. PĂ©rez-Enciso, B. Dalrymple
- BiologyBioinform.
- 1 April 2010
It is argued that RIF has universal applicability, and its use as a promising hypotheses generating tool for the systematic identification of novel TF not yet documented as critical is advocated.
A Differential Wiring Analysis of Expression Data Correctly Identifies the Gene Containing the Causal Mutation
- N. Hudson, A. Reverter, B. Dalrymple
- BiologyPLoS Comput. Biol.
- 1 May 2009
A new algorithm is proposed that correctly identifies the gene containing the causal mutation from microarray data alone and yields the correct answer, “myostatin”, the myostatin mutation that releases the brakes on Piedmontese muscle growth by translating a dysfunctional protein.
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