B. D. de Haan

Publications76
h-index29
Citations2,389
Highly Influential Citations63
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Cytokine profiles in crevicular fluid during orthodontic tooth movement of short and long durations.
BACKGROUND Orthodontic treatment induces a distortion of the extracellular matrix of the periodontium, resulting in alterations in cytoskeletal configuration. Cytokines are known to facilitate this… Expand
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Specific inulin-type fructan fibers protect against autoimmune diabetes by modulating gut immunity, barrier function, and microbiota homeostasis.
  • K. Chen, H. Chen, +7 authors J. Sun
  • Biology, Medicine
  • Molecular nutrition & food research
  • 1 August 2017
SCOPE Dietary fibers capable of modifying gut barrier and microbiota homeostasis affect the progression of type 1 diabetes (T1D). Here, we aim to compare modulatory effects of inulin-type fructans… Expand
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Chemistry and the biological response against immunoisolating alginate-polycation capsules of different composition.
Implantation of microencapsulated cells has been proposed as a therapy for a wide variety of diseases. An absolute requirement is that the applied microcapsules have an optimal biocompatibility. The… Expand
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Tissue responses against immunoisolating alginate-PLL capsules in the immediate posttransplant period.
Alginate-polylysine (PLL) capsules are commonly applied for immunoisolation of living cells for the treatment of a wide variety of diseases. Large-scale application of the technique, however, is… Expand
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DAMP production by human islets under low oxygen and nutrients in the presence or absence of an immunoisolating-capsule and necrostatin-1
In between the period of transplantation and revascularization, pancreatic islets are exposed to low-oxygen and low-nutrient conditions. In the present study we mimicked those conditions in vitro to… Expand
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Identification of TLR2/TLR6 signalling lactic acid bacteria for supporting immune regulation
Although many lactic acid bacteria (LAB) influence the consumer’s immune status it is not completely understood how this is established. Bacteria-host interactions between bacterial cell-wall… Expand
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Factors influencing the adequacy of microencapsulation of rat pancreatic islets.
The observation that only a portion of all alginate-polylysine microcapsules are overgrown after implantation suggests that physical imperfections of individual capsules, rather than the chemical… Expand
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The Impact of Lactobacillus plantarum WCFS1 Teichoic Acid D-Alanylation on the Generation of Effector and Regulatory T-cells in Healthy Mice
To date it remains unclear how probiotics affect the immune system. Bacterial envelope components may play an essential role, as these are the first to establish bacterial-host cell interactions.… Expand
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The role of pathogen-associated molecular patterns in inflammatory responses against alginate based microcapsules.
Alginate-based microcapsules are used for immunoisolation of cells to release therapeutics on a minute-to-minute basis. Unfortunately, alginate-based microcapsules are suffering from varying degrees… Expand
  • 57
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Kinetics of intraperitoneally infused insulin in rats. Functional implications for the bioartificial pancreas.
Intraperitoneal transplantation of encapsulated islets can restore normoglycemia in diabetic recipients but not normal glucose tolerance nor normal insulin responses to a physiological stimulus. This… Expand
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