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Development of pancytopenia with neutralizing antibodies to thrombopoietin after multicycle chemotherapy supported by megakaryocyte growth and development factor.
Clinical trials of thrombopoietin (TPO), the central regulator of megakaryocytopoiesis, have revealed few side effects associated with its use. We here report a case of pancytopenia associated with… Expand
Treatment of autoimmune disease by intense immunosuppressive conditioning and autologous hematopoietic stem cell transplantation.
Multiple sclerosis, systemic lupus erythematosus, and rheumatoid arthritis are immune-mediated diseases that are responsive to suppression or modulation of the immune system. For patients with severe… Expand
Phase I–II study of vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer: evidence for vorinostat-induced tubulin acetylation and Hsp90 inhibition in vivo
- B. Ramaswamy, W. Fiskus, +13 authors J. Sparano
- Breast Cancer Research and Treatment
- 1 April 2012
In preclinical models, the histone deacetylase inhibitor vorinostat sensitizes breast cancer cells to tubulin-polymerizing agents and to anti-vascular endothelial growth factor-directed therapies. We… Expand
Administration of pegylated recombinant human megakaryocyte growth and development factor to humans stimulates the production of functional platelets that show no evidence of in vivo activation.
This report describes the effect of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) on platelet production and platelet function in humans. Subjects with… Expand
Genome science: a video tour of the Washington University Genome Sequencing Center for high school and undergraduate students.
- S. Flowers, C. Easter, +5 authors S. Elgin
- Medicine, Computer Science
- Cell biology education
- 21 December 2005
Sequencing a Genome: Inside the Washington University Genome Sequencing Center" is a tour of the laboratory that follows the steps in the sequencing pipeline. Expand
Papillomaviruses, p53, and cervical cancer
Antibiotic-loaded bone cement reduces deep infection rates for primary reverse total shoulder arthroplasty: a retrospective, cohort study of 501 shoulders.
- R. J. Nowinski, R. Gillespie, Yousef Shishani, B. Cohen, G. Walch, R. Gobezie
- Journal of shoulder and elbow surgery
- 1 March 2012
BACKGROUND Deep infection after primary reverse total shoulder arthroplasty is a devastating event and has an increased incidence compared with anatomic total shoulder arthroplasty. Recent reports in… Expand
The efficacy and safety of collagenase clostridium histolyticum in the treatment of patients with moderate Dupuytren’s contracture
- D. A. McGrouther, A. Jenkins, S. Brown, R. Gerber, P. Szczypa, B. Cohen
- Current medical research and opinion
- 8 January 2014
Abstract Objective: The efficacy and safety of collagenase clostridium histolyticum (CCH) in patients with Dupuytren’s contracture (DC) was demonstrated in a program including two pivotal phase 3… Expand
Joint stiffness of the upper limb.
- B. Cohen
- 1 March 1998
In this age of modern era, the use of internet must be maximized. Yeah, internet will help us very much not only for important thing but also for daily activities. Many people now, from any level can… Expand