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Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11
The data suggest that EB size could be an important parameter in ES cell fate specification via differential gene expression of members of the noncanonical WNT pathway, according to EB size.
Human neural stem cell growth and differentiation in a gradient-generating microfluidic device.
A gradient-generating microfluidic platform for optimizing proliferation and differentiation of neural stem cells (NSCs) in culture that proliferated and differentiated in a graded and proportional fashion that varied directly with GF concentration.
Stop-flow lithography to generate cell-laden microgel particles.
This paper describes, for the first time, the fabrication of large numbers of cell-laden microgel particles using a continuous microfluidic process called stop-flow lithography (SFL), which may become a useful tool for generating cell-filled microgels for various biomedical applications.
Generation of stable concentration gradients in 2D and 3D environments using a microfluidic ladder chamber
To demonstrate the utility of the Ladder Chamber for cell migration, neutrophil chemotaxis was successfully observed in soluble chemoattractant (IL-8) gradient.
Polymerase chain reaction in microfluidic devices.
Recent developments in microfluidic-based space and time domain devices are introduced as well as various designs integrated with multiple functions for sample preparation and detection are discussed.
Microfluidic fabrication of microengineered hydrogels and their application in tissue engineering.
The current development of microfluidic-based fabrication techniques for the creation of fibers, particles, and cell-laden hydrogels are reviewed and their emerging applications in tissue engineering and regenerative medicine are highlighted.