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Patterns of somatic mutation in human cancer genomes
Cancers arise owing to mutations in a subset of genes that confer growth advantage. The availability of the human genome sequence led us to propose that systematic resequencing of cancer genomes forExpand
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Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the neoplastic transformation process. Here we engineered lymphoma-proneExpand
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Incursion of RHDV2-like variant in Great Britain
RABBIT haemorrhagic disease virus (RHDV) causes an acute, fulminating and generally fatal disease in the European rabbit ( Oryctolagus cuniculus ). It was first discovered in China in 1984 and thenExpand
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Evidence for the Circulation of Equine Encephalosis Virus in Israel since 2001
Equine encephalosis virus (EEV) distribution was thought to be limited to southern Africa until 2008 when we reported EEV in Israel. It was then assumed that the clinical presentation resembled theExpand
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Replication, Pathogenesis and Transmission of Pandemic (H1N1) 2009 Virus in Non-Immune Pigs
The declaration of the human influenza A pandemic (H1N1) 2009 (H1N1/09) raised important questions, including origin and host range [1], [2]. Two of the three pandemics in the last century resultedExpand
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The Molecular Characterization of Bovine Leukaemia Virus Isolates from Eastern Europe and Siberia and Its Impact on Phylogeny
Recent studies have shown that bovine leukemia virus (BLV) sequences can be classified into seven distinct genotypes based on full gp51 sequence. This classification was based on available sequenceExpand
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From the field to the lab — An European view on the global spread of PEDV
Abstract Porcine Epidemic Diarrhea Virus (PEDV) is a member of the genus Alphacoronavirus, in the family Coronaviridae, of the Nidovirales order and outbreaks of porcine epidemic diarrhoea (PED)Expand
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HEV infection not evident in rodents on English pig farms
Hepatitis E virus (HEV) is the cause of hepatitis E in humans, typically an acute self-limiting hepatitis but with known risk groups.1 There is now growing awareness of locally acquired infections inExpand
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Initial incursion of pandemic (H1N1) 2009 influenza A virus into European pigs
The initial incursion of pandemic (H1N1) 2009 influenza A virus (pH1N1) into a European pig population is reported. Diagnosis of swine influenza caused by pandemic virus was made during SeptemberExpand
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Identification of a transmission chain of HIV type 1 containing drug resistance-associated mutations.
We have investigated a potential transmission chain of HIV-1 with drug resistance-associated mutations between three individuals over a period of 5 years by use of cloning and sequencing of viralExpand
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