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Quality evaluation of chloroquine, quinine, sulfadoxine–pyrimethamine and proguanil formulations sold on the market in East Congo DR
Objective:  Drug quality may be poor in many regions of the world. Our first aim was to verify whether the dose of the active compounds in various antimalarial medicines on the market in East CongoExpand
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Evaluation of Artemisia annua infusion efficacy for the treatment of malaria in Plasmodium chabaudi chabaudi infected mice.
The efficacy of artemisinin (AR) against malaria has prompted its use as a tea drink in endemic communities. However, there is controversy about its efficacy in this form. Therefore we haveExpand
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Preparation of beta-artemether liposomes, their HPLC-UV evaluation and relevance for clearing recrudescent parasitaemia in Plasmodium chabaudi malaria-infected mice.
Egg phosphatidylcholine-cholesterol liposome formulations containing the antimalarial drug beta-artemether have been prepared and analyzed for their encapsulating capacity, chemical stability,Expand
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Larvicidal activity of the naphthylisoquinoline alkaloid dioncophylline A against the malaria vector Anopheles stephensi.
The larvicidal activity of dionocophylline A, a naphthylisoquinoline alkaloid derived from the tropical vine Triphyophyllum peltatum (Dioncophyllaceae), was investigated against the malaria vectorExpand
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Differential sensitivity of erythrocytic stages of the rodent malaria parasite Plasmodium chabaudi chabaudi to dioncophylline B, a highly active naphthylisoquinoline alkaloid
Abstract Four-week-old OF1 mice, infected with synchronized Plasmodium chabaudi chabaudi blood forms, were intraperitoneally injected with the naphthylisoquinoline alkaloid dioncophylline B (10 mgExpand
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Influence of the host photoperiodicity on the schizogonic cycle and the synchronism of the rodent malaria parasite Plasmodium chabaudi chabaudi
This study intended to determine whether LD (Light:Dark) regimens different from the usual 12:12 hours could impair the schizogonic cycle and the synchronism of the rodent malaria parasite PlasmodiumExpand
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A comparison of the stage-specific efficacy of chloroquine, artemether and dioncophylline B against the rodent malaria parasite Plasmodium chabaudi chabaudiin vivo
Abstract. Chloroquine, artemether and dioncophylline B efficacy against Plasmodium chabaudi was compared. One intraperitoneal injection (10 mg/kg body weight) was given daily over 3 consecutive daysExpand
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Chronobiology of Plasmodium chabaudi chabaudi: analysis of hourly recorded total and differential parasitaemia during a schizogonic cycle.
Detailed total and differential parasitaemia curves of asexual Plasmodium chabaudi chabaudi erythrocytic stages were recorded and analysed. Female, inbred, CBA/Ca mice were infected with the virulentExpand
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  • Open Access
Structure, absolute configuration, and conformation of the antimalarial drug artesunate
The crystal and molecular structure of the antimalarial compound artesunate has been determined by direct methods. Crystals are orthorhombic, P212121, a = 9.8371(12), b = 10.517(2), c = 18.7594(5) Å,Expand
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Surveillance Entomologique des Vecteurs du Plasmodium dans les Gites Larvaires en Territoire de Kabare, Est de la RD Congo ( Entomologic Survey of the Vectors of Paludism in Resting Place Larvas in
The survey of mosquito larvae in various resting places of 2011 - 2012 to Kabare, South-Kivu, Eastern of the R D Congo, interested the phase of the aquatic development of these vectors of theExpand
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