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- Publications
- Influence
An overview on fermentation, downstream processing and properties of microbial alkaline proteases
- R. Gupta, Q. Beg, S. Khan, B. Chauhan
- Biology, Medicine
- Applied Microbiology and Biotechnology
- 12 October 2002
Abstract. Microbial alkaline proteases dominate the worldwide enzyme market, accounting for a two-thirds share of the detergent industry. Although protease production is an inherent property of all… Expand
Preparation and evaluation of glibenclamide-polyglycolized glycerides solid dispersions with silicon dioxide by spray drying technique.
- B. Chauhan, S. Shimpi, A. Paradkar
- Chemistry, Medicine
- European journal of pharmaceutical sciences…
- 1 October 2005
Solid dispersions (SDs) of glibenclamide (GBM); a poorly water-soluble drug and polyglycolized glycerides (Gelucire with the aid of silicon dioxide (Aerosil 200); as an adsorbent, were prepared by… Expand
Cyclodextrins: application in different routes of drug administration.
- S. Shimpi, B. Chauhan, Prajakta C. Shimpi
- Chemistry, Medicine
- Acta pharmaceutica
- 1 June 2005
The objective of this review article is to explain the use of cyclodextrin in the different routes of drug administration. The article gives the chemistry of cyclodextrins and addresses the issue of… Expand
Preparation and evaluation of diltiazem hydrochloride-gelucire 43/01 floating granules prepared by melt granulation
- S. Shimpi, B. Chauhan, K. Mahadik, A. Paradkar
- Chemistry, Medicine
- AAPS PharmSciTech
- 12 July 2004
The basic objective of this study was to explore the application of Gelucire 43/01 for the design of multi-unit floating systems of a highly water-soluble drug diltiazem HCl. Diltiazem HCl-Gelucire… Expand
Preparation and characterization of etoricoxib solid dispersions using lipid carriers by spray drying technique
- B. Chauhan, S. Shimpi, A. Paradkar
- Materials Science, Medicine
- AAPS PharmSciTech
- 19 October 2005
The basic objectives of this study were to prepare and characterize solid dispersions of poorly water-soluble drug etoricoxib using lipid carriers by spray drying technique. The properties of solid… Expand
Effect of potassium chloride and cationic drug on swelling, erosion and release from κ-carrageenan matrices
- S. Naim, B. Samuel, B. Chauhan, A. Paradkar
- Chemistry, Medicine
- AAPS PharmSciTech
- 9 March 2004
The basic objective of this work was to study the effect of model cationic drug metformin HCl on swelling and erosion and, in turn, the release of KCl and drug itself, from the κ-carrageenan… Expand
Preparation and evaluation of ibuprofen beads by melt solidification technique.
- A. Paradkar, M. Maheshwari, A. Ketkar, B. Chauhan
- Materials Science, Medicine
- International journal of pharmaceutics
- 14 April 2003
A novel single step melt solidification technique was developed for ibuprofen. DSC studies designed to elucidate the effect of isothermal holding time showed that the extent of crystallization… Expand
Preparation and characterization of flurbiprofen beads by melt solidification technique
- A. Paradkar, M. Maheshwari, A. Tyagi, B. Chauhan, S. Kadam
- Materials Science, Medicine
- AAPS PharmSciTech
- 16 December 2003
Amelt solidification technique has been developed to obtain sustained-release waxy beads of flurbiprofen. Low glass transition temperature (tg) and shear-induced crystallization of flurbiprofen made… Expand
Stabilization and Improved in Vivo Performance of Amorphous Etoricoxib using Gelucire 50/13
- S. Shimpi, B. Chauhan, K. R. Mahadik, A. Paradkar
- Chemistry, Medicine
- Pharmaceutical Research
- 22 September 2005
PurposeAmorphous drugs have gained importance because of their advantageous biopharmaceutical properties; however, their stabilization remains a challenge. The purpose of this work was to stabilize… Expand
Preparation and characterization of ibuprofen-cetyl alcohol beads by melt solidification technique: effect of variables.
- M. Maheshwari, A. Ketkar, B. Chauhan, V. Patil, A. Paradkar
- Chemistry, Medicine
- International journal of pharmaceutics
- 11 August 2003
Ibuprofen (IBU) exhibits short half-life, poor compressibility, flowability and caking tendency. IBU melt has sufficiently low viscosity and exhibits interfacial tension sufficient to form droplet… Expand