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Binding, internalization, and lysosomal association of 125I-glucagon in isolated rat hepatocytes. A quantitative electron microscope autoradiographic study.
When 125I-glucagon is incubated with freshly isolated rat hepatocytes and studied by quantitative electron microscope autoradiography, the labeled material localizes to the plasma membrane of theExpand
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Glucose metabolism in experimental hyperthyroidism: intact in vivo sensitivity to insulin with abnormal binding and increased glucose turnover.
The characteristics of the dose response of insulin on the glucose turnover rate and erythrocyte insulin binding parameters were determined in five normal men before and during experimentally inducedExpand
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Type 1 diabetes mellitus and homocyst(e)ine.
High Homocyst(e)ine levels (H) have been recently recognized as a risk factor for atherosclerosis. Patients with Diabetes Mellitus (DM) are prone to atherosclerosis. Therefore, this study wasExpand
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Inhibitory effects of metformin on insulin and glucagon action in rat hepatocytes involve post-receptor alterations.
The effect of the hypoglycaemic biguanide, metformin, on insulin binding and insulin action was investigated in rat hepatocyte monolayers. The binding of insulin was not modified in cultured cellsExpand
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Assessment of cardiac arrhythmic risk in diabetic patients using QT dispersion abnormalities.
The purpose of this study was to assess the abnormalities and prevalence of QT dispersion in 154 diabetic patients (DP) who underwent a standard 12-lead ECG. QT interval was measured from theExpand
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Distinguishing Colonization From Infection With Staphylococcus aureus in Diabetic Foot Ulcers With Miniaturized Oligonucleotide Arrays
OBJECTIVE To extend our previous work on evaluating the use of oligonucleotide arrays to discriminate colonization from infection owing to Staphylococcus aureus in diabetic foot ulcers (DFUs).Expand
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Toxic hepatitis induced by antithyroid drugs: four cases including one with cross-reactivity between carbimazole and benzylthiouracil.
OBJECTIVE This study was conducted to assess the occurrence of hepatic adverse effects encountered with antithyroid drugs. METHODS Retrospective review of medical records of 236 patients withExpand
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Distribution of edin in Staphylococcus aureus isolated from diabetic foot ulcers.
Staphylococcus aureus is both a common colonizer of human skin and the most frequently isolated pathogen in diabetes foot infections (DFIs). The spread of DFI to soft tissue and bony structures is aExpand
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Somatostatin: lack of effect of cyclic AMP release and amino acid transport in isolated rat hepatocytes.
The aim of the present study was to determine whether or not somatostatin can directly affect amino acid transport and cyclic AMP (cAMP) release in isolated rat hepatocytes. Somatostatin at 1.5Expand
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Glucocorticoid and catecholamine stimulation of amino acid transport in rat hepatocytes: Synthesis of a high-affinity component
The kinetic properties of glucocorticoid and catecholamine stimulation of amino acid transport in freshly isolated rat hepatocytes were investigated. In the basal state (i.e., with hepatocytesExpand
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