Chemical Composition and Bioactivity of Essential Oil from Blepharocalyx salicifolius
- F. B. Furtado, B. C. Borges, A. Fernandes Júnior
- BiologyInternational Journal of Molecular Sciences
- 1 January 2018
Essential oil from B. salicifolius showed promising biological activities and is therefore a source of molecules to be exploited in medicine or by the pharmaceutical industry.
A high throughput analysis of cytokines and chemokines expression during the course of Trypanosoma cruzi experimental oral infection.
- A. A. Rodrigues, A. F. Notário, C. V. da Silva
- BiologyActa Tropica
- 1 May 2016
Chemokines and the extracellular matrix: Set of targets for tumor development and treatment.
- Paulo Henrique Rosa da Silva, B. C. Borges, I. A. Uehara, Luiz Ricardo Soldi, R. A. de Araújo, M. J. B. Silva
- Biology, ChemistryCytokine
- 7 May 2021
A comparative study on the leishmanicidal activity of the L-amino acid oxidases BjussuLAAO-II and BmooLAAO-II isolated from Brazilian Bothrops snake venoms.
- L. G. Barbosa, T. R. Costa, R. Rodrigues
- BiologyInternational Journal of Biological…
- 23 November 2020
Increased ROS generation causes apoptosis-like death: Mechanistic insights into the anti-Leishmania activity of a potent ruthenium(II) complex.
- M. S. Costa, Y. Gonçalves, K. G. Yoneyama
- Chemistry, BiologyJournal of Inorganic Biochemistry
- 1 June 2019
Genotoxic effects of BnSP-6, a Lys-49 phospholipase A2 (PLA2) homologue from Bothrops pauloensis snake venom, on MDA-MB-231 breast cancer cells.
- Makswell Almeida Silva, D. Lopes, R. Rodrigues
- Biology, ChemistryInternational Journal of Biological…
- 1 October 2018
Mechanisms of Infectivity and Evasion Derived from Microvesicles Cargo Produced by Trypanosoma cruzi
- B. C. Borges, I. A. Uehara, L. O. S. Dias, P. Brígido, C. V. da Silva, M. J. B. Silva
- BiologyFrontiers in Cellular and Infection Microbiology
- 22 November 2016
The molecular content of these vesicles is composed of several molecules that take place during parasite-host cell interaction and contribute to the parasite-driven mechanism of evasion from the host immune system.
Trypanosoma cruzi P21: a potential novel target for chagasic cardiomyopathy therapy
- T. L. Teixeira, F. Machado, C. V. da Silva
- Biology, MedicineScientific Reports
- 17 November 2015
Results indicated that rP21 can recruit immune cells induce myeloperoxidase and IL-4 production and decrease blood vessels formation compared to controls in vitro and in vivo, and T. cruzi P21 may be a potential target for the development of P21 antagonist compounds to treat chagasic cardiomyopathy.
Insights into the antiviral activity of phospholipases A2 (PLA2s) from snake venoms
- S. Teixeira, B. C. Borges, D. Lopes
- BiologyInternational Journal of Biological…
- 19 July 2020
Copaifera spp. oleoresins impair Toxoplasma gondii infection in both human trophoblastic cells and human placental explants
- S. Teixeira, Guilherme de Souza, E. Ferro
- BiologyScientific Reports
- 16 September 2020
It is demonstrated that oleoresins from different species of Copaifera genus were able to reduce T. gondii intracellular proliferation, adhesion, and invasion and reduce parasite replication and TNF-α release in villous explants.
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