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The mechanical basis of morphogenesis. I. Epithelial folding and invagination.
TLDR
The objective of this paper is to demonstrate that the model, based on the local behavior of individual cells, generates a propagating contraction wave which is sufficient to explain the globally coherent morphogenetic infolding of a wide variety of embryonic epithelia. Expand
A New Compartment at Stereocilia Tips Defined by Spatial and Temporal Patterns of Myosin IIIa Expression
TLDR
A previously unrecognized molecular compartment at the distal end of stereocilia, the site of actin polymerization as well as operation of the mechanoelectrical transduction apparatus is revealed. Expand
Microtubules and microfilaments in newt neuralation.
  • B. Burnside
  • Biology, Medicine
  • Developmental biology
  • 1 November 1971
TLDR
Electron microscopy of presumptive neural cells has been carried out in an attempt to understand the mechanism of morphogenetic cell shape changes and several observations suggest that microtubules contribute to cell elongation by some form of transport mechanism. Expand
Dopaminergic Regulation of Cone Retinomotor Movement in Isolated Teleost Retinas: I. Induction of Cone Contraction Is Mediated by D2 Receptors
TLDR
3,4‐dihydroxyphenylethylamine (dopamine) mimics the effect of light by inducing light‐adaptive retinomotor movements in cones, rods, and RPE cells by activating D2 receptors, suggesting that dopamine plays a role in both light and circadian regulation of retinmotor movements. Expand
Microtubules and Microfilaments in Amphibian Neurulation
TLDR
Evidence is presented which suggests that microfilament bundles play an active role in apical constriction, and that this localized contraction is produced by filament sliding. Expand
Localization of kinesin superfamily proteins to the connecting cilium of fish photoreceptors.
TLDR
It is proposed that these putative kinesin superfamily proteins may be involved in the translocation of material between the rod inner and outer segments. Expand
Characterization of peripherin/rds and rom-1 transport in rod photoreceptors of transgenic and knockout animals.
TLDR
The presence of truncated peripherin/rds-GFP in the outer segment supports previous evidence that peripherin-rds mice form homotetramers for outer segment targeting and suggests that rom-1 may possess its own sorting and transport signals. Expand
Cloning and chromosomal localization of a human class III myosin.
TLDR
The cloning and chromosomal localization of a human class III myosin, MYO3A, from retina and a retinal pigment epithelial cell line is reported and it is suggested that the human homologue MYO2A may also play a role in photoreceptor function and/or maintenance. Expand
Myo3A, one of two class III myosin genes expressed in vertebrate retina, is localized to the calycal processes of rod and cone photoreceptors and is expressed in the sacculus.
TLDR
The numerous IQ motifs may play a structural or signaling role in the Myo3A, and its localization to calycal processes indicates that this myosin mediates a local function at this site in vertebrate photoreceptors. Expand
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