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Isoenzyme analysis of 35 Toxoplasma gondii isolates and the biological and epidemiological implications.
- M. Dardé, B. Bouteille, M. Pestre-Alexandre
- Biology, Medicine
- The Journal of parasitology
- 1 October 1992
Fifteen enzyme systems were studied after isoelectrofocusing of tachyzoite extracts in polyacrylamide or agarose gels and their combination allows the description of 5 zymodemes among the 35 T. gondii isolates, which are less pathogenic to mice and produced oocysts. Expand
Treatment of human African trypanosomiasis.
The challenge presented by human African trypanosomiasis must be taken up by developed countries because it is geographically limited and the absence of a non-toxic treatment that is easily administered, reasonably priced, and effective at every stage of the disease, especially the neurological. Expand
Treatment perspectives for human African trypanosomiasis
- B. Bouteille, Odile Oukem, S. Bisser, M. Dumas
- Fundamental & clinical pharmacology
- 1 April 2003
A pentamidine analog that offers hope for the replacement of injectable pent amine with an orally administered drug is in the clinical development phase and orally administered eflornithine is also slated for reevaluation. Expand
Seroprevalence of cysticercosis in Bénin.
- D. Houinato, B. Ramanankandrasana, +5 authors B. Bouteille
- Transactions of the Royal Society of Tropical…
- 1 November 1998
A progressive increase in seroprevalence with increasing age was found and the public health importance of cysticercosis in Bénin was demonstrated. Expand
Cysticercosis as a Major Risk Factor for Epilepsy in Burundi, East Africa
- G. Nsengiyumva, M. Druet‐Cabanac, B. Ramanankandrasana, B. Bouteille, L. Nsizabira, P. Preux
- 1 July 2003
The objective was to evaluate the role of cysticercosis in epilepsy in Burundi and results of studies on the impact of neurocysticercoses on epilepsy in Africa are inconsistent. Expand
Epidemiological study of neuro-cysticercosis in northern Togo (West Africa).
In april 1987, an epidemiologic study in Northern Togo was carried out in order to evaluate the prevalence of cysticercosis and epilepsy and investigate possible connections between these two illnesses. Expand
Human Neurocysticercosis: Comparison of Different Diagnostic Tests Using Cerebrospinal Fluid
- L. Michelet, A. Fleury, +4 authors B. Bouteille
- Journal of Clinical Microbiology
- 10 November 2010
Compared immunodiagnostic assays with the detection of parasite DNA by PCR amplification of a repetitive element of the parasite genome in the cerebrospinal fluid of 121 radiologically and clinically characterized NC patients can help in the selection of different individual assays or combinations of assays to be used in NC diagnosis according to different requirements. Expand
Megazol combined with suramin: a chemotherapy regimen which reversed the CNS pathology in a model of human African trypanosomiasis in mice
- B. Enanga, M. Keita, G. Chauvière, M. Dumas, B. Bouteille
- Biology, Medicine
- Tropical medicine & international health : TM…
- 1 September 1998
Results suggest that the megazol‐suramin combination combination treatment reversed the central nervous system pathology in this model of HAT, indicating that this chemotherapy regimen was curative. Expand
[Cysticercosis and neurocysticercosis: epidemiological survey in North Togo].
- M. Dumas, K. Grunitzky, +6 authors M. P. Alexandre
- Biology, Medicine
- Bulletin de la Societe de pathologie exotique
An epidemiologic survey was carried out by a team of medical doctors working in the Kozah district of North Togo during April 1987 and cysticercosis proved to be the cause of 29.5% epileptic sufferers, onset occurring after the age of 50 in 66% of these patients. Expand
Human macrophage tumor necrosis factor (TNF)-alpha production induced by Trypanosoma brucei gambiense and the role of TNF-alpha in parasite control.
TNF-alpha is involved in parasite growth control in human African trypanosomiasis, and a direct dose-dependent lytic effect of TNF- alpha on purified parasites was observed. Expand