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Myocardial Injury after Noncardiac Surgery: A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes
Background:Myocardial injury after noncardiac surgery (MINS) was defined as prognostically relevant myocardial injury due to ischemia that occurs during or within 30 days after noncardiac surgery.Expand
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Aspirin in patients undergoing noncardiac surgery.
BACKGROUND There is substantial variability in the perioperative administration of aspirin in patients undergoing noncardiac surgery, both among patients who are already on an aspirin regimen andExpand
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Risks to healthcare workers following tracheal intubation of patients with COVID‐19: a prospective international multicentre cohort study
Healthcare workers involved in aerosol‐generating procedures, such as tracheal intubation, may be at elevated risk of acquiring COVID‐19. However, the magnitude of this risk is unknown. We conductedExpand
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Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery.
CONTEXT Of the 200 million adults worldwide who undergo noncardiac surgery each year, more than 1 million will die within 30 days. OBJECTIVE To determine the relationship between the peakExpand
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Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery
Importance Little is known about the relationship between perioperative high-sensitivity troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac surgery (MINS).Expand
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A meta‐analysis of the utility of pre‐operative brain natriuretic peptide in predicting early and intermediate‐term mortality and major adverse cardiac events in vascular surgical patients
We conducted a meta‐analysis of the utility of pre‐operative B‐type natriuretic peptide (BNP) and N‐terminal‐pro B‐type natriuretic peptide in predicting early (< 30 days) and intermediate (< 180Expand
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Clonidine in patients undergoing noncardiac surgery.
BACKGROUND Marked activation of the sympathetic nervous system occurs during and after noncardiac surgery. Low-dose clonidine, which blunts central sympathetic outflow, may prevent perioperativeExpand
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The predictive ability of pre-operative B-type natriuretic peptide in vascular patients for major adverse cardiac events: an individual patient data meta-analysis.
OBJECTIVES The aims of this study were to perform an individual patient data meta-analysis of studies using B-type natriuretic peptides (BNPs) to predict the primary composite endpoint of cardiacExpand
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The South African Surgical Outcomes Study: A 7-day prospective observational cohort study.
  • B. Biccard, T. Madiba
  • Medicine
  • South African medical journal = Suid-Afrikaanse…
  • 18 September 2015
BACKGROUND Non-cardiac surgical morbidity and mortality is a major global public health burden. Sub-Saharan African perioperative outcome data are scarce. South Africa (SA) faces a unique publicExpand
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The pathophysiology of peri‐operative myocardial infarction
It is generally believed that plaque rupture and myocardial oxygen supply‐demand imbalance contribute approximately equally to the burden of peri‐operative myocardial infarction. This reviewExpand
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