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GABAB-receptor subtypes assemble into functional heteromeric complexes
B-type receptors for the neurotransmitter GABA (γ-aminobutyric acid) inhibit neuronal activity through G-protein-coupled second-messenger systems, which regulate the release of neurotransmitters andExpand
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Molecular structure and physiological functions of GABA(B) receptors.
GABA(B) receptors are broadly expressed in the nervous system and have been implicated in a wide variety of neurological and psychiatric disorders. The cloning of the first GABA(B) receptor cDNAs inExpand
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Molecular Structure and Physiological Functions of GABAB Receptors
GABAB receptors are broadly expressed in the nervous system and have been implicated in a wide variety of neurological and psychiatric disorders. The cloning of the first GABAB receptor cDNAs in 19...
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Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.
GABA (gamma-amino-butyric acid), the principal inhibitory neurotransmitter in the brain, signals through ionotropic (GABA(A)/ GABA(c)) and metabotropic (GABA(B)) receptor systems. Here we report theExpand
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Cloning of a novel glutamate receptor subunit, GluR5: Expression in the nervous system during development
We have isolated cDNAs encoding a glutamate receptor subunit, designated GluR5, displaying 40%-41% amino acid identity with the kainate/AMPA receptor subunits GluR1, GluR2, GluR3, and GluR4. ThisExpand
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Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice
l-glutamate, the neurotransmitter of the majority of excitatory synapses in the brain, acts on three classes of ionotropic receptors: NMDA (N-methyl-d-aspartate), AMPAExpand
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Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors
GABA (γ-amino-butyric acid), the principal inhibitory neurotransmitter in the brain, signals through ionotropic (GABAA/GABAC) and metabotropic (GABAB) receptor systems. Here we report the cloning ofExpand
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GABAB receptors - the first 7TM heterodimers.
Evidence supports the existence of pharmacological subtypes of GABAB receptors24xKerr, D.I.B. and Ong, J. Pharmacol. Ther. 1995; 67: 187–246Crossref | PubMed | Scopus (192)See all References24. AtExpand
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Trace Amine-Associated Receptor 1 Modulates Dopaminergic Activity
The recent identification of the trace amine-associated receptor (TAAR)1 provides an opportunity to dissociate the effects of trace amines on the dopamine transporter from receptor-mediated effects.Expand
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The GABAB1b Isoform Mediates Long-Lasting Inhibition of Dendritic Ca2+ Spikes in Layer 5 Somatosensory Pyramidal Neurons
The apical tuft of layer 5 pyramidal neurons is innervated by a large number of inhibitory inputs with unknown functions. Here, we studied the functional consequences and underlying molecularExpand
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