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Vasculoprotective properties of the endothelial glycocalyx: effects of fluid shear stress
The endothelial glycocalyx exerts a wide array of vasculoprotective effects via inhibition of coagulation and leucocyte adhesion, by contributing to the vascular permeability barrier and by mediatingExpand
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Impaired glycocalyx barrier properties contribute to enhanced intimal low-density lipoprotein accumulation at the carotid artery bifurcation in mice
The glycocalyx contributes to the barrier properties of vascular endothelium, and recently, we reported using electron microscopy that glycocalyx is diminished at lesion prone sites in arterialExpand
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Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease
Heparanase has regulatory roles in various processes, including cell communication, gene transcription and autophagy. In addition, it is the only known mammalian endoglycosidase that is capable ofExpand
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Role for glycocalyx perturbation in atherosclerosis development and associated microvascular dysfunction
The importance of the endothelial glycocalyx for vascular homeostasis is becoming more and more evident. This review addresses the potential relation between a damaged glycocalyx and the process ofExpand
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Abstract 638: Flow Modulates the Endothelial Expression of Neuronal Guidance Cues
Disturbed hemodynamic conditions lead to impaired homeostasis of the vascular endothelium and, subsequently, influx and retention of monocytes in the arterial wall. Emerging data suggest that, asideExpand