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SDH5, a Gene Required for Flavination of Succinate Dehydrogenase, Is Mutated in Paraganglioma
Tapping the Mitochondrial Proteome Mitochondria produce the energy that cells need to survive, function, and divide. A growing list of human disorders has been traced to defects in mitochondrialExpand
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Masses of the salivary gland region in children.
BACKGROUND Noninflammatory masses of the salivary gland region in children are extremely rare. Therefore, very few published individual and institution-based experiences exist. DESIGN RetrospectiveExpand
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Head and Neck Soft Tissue Sarcomas: A Multivariate Analysis of Outcomes
BackgroundSoft tissue sarcomas of the head and neck region represent a rare group of tumors of which a limited number of published individual- and institution-based experiences exist.MethodsWeExpand
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Relative contributions of radiation and cisplatin-based chemotherapy to sensorineural hearing loss in head-and-neck cancer patients.
PURPOSE To investigate the risk of sensorineural hearing loss (SNHL) in patients with head-and-neck cancer and treated with radiation therapy (RT) or concomitant cisplatin-based chemoradiation, theExpand
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Anterior skull base surgery for malignant tumors: A multivariate analysis of 27 years of experience
Few studies have examined prognostic factors that have an impact on outcomes in anterior skull base surgery by multivariate analysis.
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Utility of BRAF V600E mutation detection in cytologically indeterminate thyroid nodules
Background Fine needle aspiration (FNA) is widely utilized for evaluation of patients with thyroid nodules. However, approximately 30% are indeterminate for malignancy. Recently, a mutation in theExpand
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Detection of BRAF V600E activating mutation in papillary thyroid carcinoma using PCR with allele-specific fluorescent probe melting curve analysis
Background: A single hotspot mutation at nucleotide 1799 of the BRAF gene has been identified as the most common genetic event in papillary thyroid carcinoma (PTC), with a prevalence of 29–83%. Aims:Expand
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Detection of human papillomavirus using hybrid capture 2 in oral brushings from patients with oropharyngeal squamous cell carcinoma.
Detection of high-risk (HR) human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (SCC) has important prognostic implications; patients exhibit improved survival compared with patientsExpand
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Increased protein nitrosylation in head and neck squamous cell carcinogenesis
Nitric oxide (NO·) and its metabolic byproducts are implicated in carcinogenesis. We examined a marker of NO·‐species' pathologic protein nitrosylation, nitrotyrosine, during head and neck squamousExpand
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B-RAF V600E mutational analysis of fine needle aspirates correlates with diagnosis of thyroid nodules
Objective: A mutation of B-type RAF kinase (B-RAF) represents the most common genetic alteration in papillary thyroid cancer (PTC), possibly signifying a more aggressive biology. Fine needleExpand
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